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Clinical case of primary chronic adrenal cortex insufficiency (Addison’s disease)

https://doi.org/10.51523/2708-6011.2025-22-4-17

Abstract

Adrenal insufficiency is a relatively rare but serious disease characterized by decreased production of glucocorticoids and/or mineralocorticoids and adrenal androgens due to adrenal destruction or lack of its stimulation. This condition is characterized with subtle and rather nonspecific signs and symptoms that develop over weeks to months, and often go unnoticed, leading to delays in diagnosis [1]. A high level of clinical suspicion and diagnostic knowledge are required for diagnosis.

The article presents a clinical case of primary chronic adrenal cortex insufficiency in a middle-aged patient. An analysis of literary sources, clinical data, and laboratory test results was performed.

About the Authors

A. V. Pronevich
Gomel State Medical University
Беларусь

Anna V. Pronevich - Senior Lecturer at the Department of Outpatient Therapy and General Medical Practice with the course of Advanced Training and Retraining, Gomel State Medical University.

Gomel



O. L. Nikiforova
Gomel State Medical University
Беларусь

Olga L. Nikiforova - Senior Lecturer at the Department of Outpatient Therapy and General Medical Practice with the course of Advanced Training and Retraining, Gomel State Medical University.

Gomel



References

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Review

For citations:


Pronevich A.V., Nikiforova O.L. Clinical case of primary chronic adrenal cortex insufficiency (Addison’s disease). Health and Ecology Issues. 2025;22(4):135-140. (In Russ.) https://doi.org/10.51523/2708-6011.2025-22-4-17

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ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)