The comparative analysis of existing ways of prognosis of the complicated development of the acute pancreatitis is made, the modern way of prognosis with use of artificial neural networks (ANN) is described in this article. By results of research, accuracy of results at artificial neural modeling makes 90%, specificity - 96%. Method allows improving degree of accuracy of the prognosis. ANN optimizes early diagnostics infected pancreatic necrosis and help to choose adequate medical tactics.

The rhythm disturbances is the most frequently complication after general surgery and is associated with significant morbidity, longer hospital stay, and higher costs. The studies about reason and mechanism of the development arrhythmias on background of surgical pathology is not enough, and, sometimes, inconsistent. The knowledge of arrhythmogenesis beside given categories patient will reduce risk of the development arrhythmias, and raise efficiency of the treatment.

Retrospective review of surgical repair results in patients with cleft palate and lip has been conducted on the base of Gomel Regional Hospital. The obtained results revealed a change in surgical approach used to repair cleft palate and lip from single-stage methods to double-stage methods, which allow to achieve aesthetic and functional results better than single-stage methods. Necessity to improve management of patients with cleft palate and lip, which should include better cooperation of specialists form different specialties, has been reemphasized.

It was studied the early and long-term results of staged reconstruction with silicon T-tube of 37 patients with cicatricial trachtal stenosis. In 36 (97,3%) patients tracheal stenosis was iatrogenic after respiratory reanimation. Indications for staged tracheal reconstruction with silicon T-tube and techniques of the tracheoplasty with patients own rib cartilage are given. Complications of the tracheal reconstructions were granulations (37,8%), restenosis (24,3%) and wound infection (5,4%). Ninety two percent patients showed good and satisfactory long-term results.

The active forms of the oxygen play the important role to the pathogenesis infectious-inflammatory processes. The processes free radical's oxidations participate in process of the damage of the hutches breach their function. The high activity free radical brings about change the metabolism of the oxides of the nitrogen, breach function endothelium. The reduction antioxidants protection of the hutches liver under infectious-inflammatory process leads to reinforcement cytolysis, reduction to activities enzymatic systems, participating in biotransformation medicinal material, for instance ceftriaxone. The breach function ферментных of the systems, ruin hepatocyts, reduction to transport function of the albumin, can bring about significant braking biotransformation ceftriaxone, change pharmacological and toxically effect medicine under sharp infectious-inflammatory process.

In article results of research of current of a wound process at patients with pyoinflammatory diseases of soft tissues are submitted during treatment with application in a complex of actions local ozonotherapy with the help of the modified device for a local darsonvalization «Блик». Object of observation were 174 patients with acute and chronic pyoinflammatory diseases of soft tissues. All patients depending on the diagnosis and the applied way of treatment in regular intervals divided into 4 groups. The estimation of character of current of a wound process was carried out by clinical, laboratory, bacteriological and tool methods. It fixed, that on a background local озонотерапии at patients faster cupping of a pain, earlier clarification of wounds from a purulent-necrotic strike and a bacterial microflora, faster occurrence of granulations and a cuticularization wound defect was observed.

The analytical review of references on the effectiveness of hepatoprotectors of different groups was made. The various classifications and clinical pharmacology of hepatoprotectors were reviewed. The analysis of preparations effectiveness of new groups was done.

The results of enzyme-linked immunosorbent assay (ELISA) for detection of antibodies to hepatitis C virus (HCV) spectrum in 191 patients with HCV-infection, including 176 patients with chronic hepatitis C (CHC) and 15 patients with acute hepatitis C (AHC), and in 85 blood donors with the help of ELISA kit for confirmation of antibodies to hepatitis C virus detection produced in Gomel State Medical University are represented. The sensitivity and specificity parameters of the ELISA kit were calculated in comparison with RNA HCV detection by means of polymerase chain reaction (PCR) method. The specificity was 100%, sensitivity - 98%. In 92.2% of patients with CHC and in 73.3% of those with AHC antibodies to Core, NS3 and NS4 HCV proteins simultaneously were revealed. When anti-NS5 were detected, the ALT levels were higher.

The present paper presents criteria which allow to identify risk groups including moderately expressed cognitive disorders with the localization of cerebral infarction in the right medial cerebral artery and some changes of lipid metabolism parameters (criteria triad), with the possible transformation of the detected disorders into stroke dementia. These patients are recommended treatment at ambulatory-polyclinacal and home stages.

The aim of the study was the investigation of the dependence neuropsychological and the vegetative status at patients with chronic cerebrovascular insufficiency for what 47 patients in the age from 64 till 88 years have been surveyed. It was shown decrease of the tonus of sympathetic nervous system that was clinically shown by deterioration of performance of dynamic tests and recognition of complex designs has been revealed. The analysis of reactivity has revealed a possible of the adaptation reserve.

The given article deals with the data about hemodynamic disorders of central and cerebral blood flow in children with primary arterial hypotensia in different conditions clinorthostatic sign. Systemic blood circulation peripheral vessels dilatation, cerebral vessels evident hypotonia of a small gauge and difficult venous return are the main causes of asthenic and cephalgic syndrome in sick children. Heart morphofunctional particularities in patients with primary arterial hypotensia are determined.

The anthropometric measurements of 255 boys at the age of 7 to 17 has been performed. Key measurements included body mass, chest circumference, shoulder and pelvis width dimension. The received data was statistically processed. Certain features of physical development, specific for Gomel region, were revealed.

In the short review article considered peculiarity of the various extraction and culture methods of the hematopoietic stem cells CD34+, carried out their comparative analysis. The main directions of the cellular therapy development detailed. An advantages of immunomagnetic separations method as compared with other methods described. The results of pilot experiences of stem cells extraction in Central Research Laboratory of Gomel’s state medical university represented.

The present review highlights biological and biochemical properties of ozone which presumes brand new solution of actual aspects of contemporary medicine. This proves once again that ozone therapy in the Republic of Belarus will take its place among non-medical natural factors in therapeutic set of the number of diseases.

30 skilled sportsmen, and 15 not training persons were examined by the method of bioimpedance analysis of the body composition. Analysis of the main parameters of the sportsmen body composition is given. The data of fatty mass, active cellular mass, lean mass differ from the same parameters of not training persons. The most variable age factor of the sportsmen body composition is the fatty mass. The influence of the methodical error the bioimpedance analysis on the body composition parameters was studied.

Based оn the data yielded by immunohistochemical and morphometric research, expressions of smooth muscle actin in the prostate cancer were analysed. It was revealed, that its low expression in a stroma of neoplasms and in walls of vessels is more characteristic of low-grade cancers and tumours with higher metastatic potential. In addition, low-grade cancers featured disturbance of the formation of vessels’ smooth muscle skeleton, decrease of its thickness, appearance of discontinuity and defects of smooth muscle layer, which reflect imperfection of neoangiogenesis and can be a prognostic marker of a neoplasm.

By the example of white laboratory rats are considered pathomorphological characteristics experimental osteoartrozis in various terms of development of pathological process. In original research the way of formation of pathological changes in a joint and methods of a morphological estimation of fabric changes which allow to give the objective characteristic morphogenetic processes is offered.

In the review of the literature modern data on mechanisms of development of placentary insufficiency and opportunities of her treatment with the help new bioregular means - diavitol are resulted.

Comparative analysis of the hemolytic action of ethylene glycole was made in the experiments carried out on donor blood and in the acute experiments on white not purebred male rats. It was revealed that action of ethylene glycole in the concentration of 0,2% on the osmotic resistance of erythrocytes is analogous to the action of ethylene glycole administrated to a rate intrastomachaly in the amount of 0,5 ml on 100 g of body weight.

In original research the modern sight at problems of desease and death rate of liquidators of failure at the Chernobyl atomic power station, living in three regions of Byelorussia is offered. The data statistical and pathomorphological researches are used.

In the work the morphometric analysis of a myocardium tissue of the experimental animals, undergone impact of incorporated radionuclides has been carried out. The given stress factor causes the adaptable reaction demonstrated in a complex biochemical and morphfunctional changes. The revealed structural infringements are the following: decrease in muscular mass of myocardium tissue and cardiomiocytes quantity reduction on a background of a hypertrophy of their nuclei. Reduced to collagenazin and growth of connective tissues strom and mass dilation of a coronary capillary network. The arisen structural infringements can serve as the precondition of development of a pathology development.

The analysis of a condition of superficial water bodies of the Republic of Belarus is done. In connection with development of tourism the condition of the water bodies used in the recreational purposes is actual. The principal cause of their unsatisfactory condition is insufficiently cleared sewage. In this connection the prospect of application of new methods of clearing and disinfecting of sewage is offered.

In order to identify the possibility of time regularity in the appearance of such ulcer complication as perforation, a study of 2200 cases of perforating ulcer incidence within the period of 1986-2005 among Gomel population has been performed. The study results have not confirmed the widespread theory of prevailing frequency of gastroduodenal ulcer perforations in spring and autumn. Dominant friqenst of perforated peptic ulcers (PPU) can be marked in any season of the year. The stated decrease in incidens of PPU - is taking place in winter season.