Adrenal adenoma with mixed hormonal secretion
M. A. Duka,
Ya. L. Naumenava,
M. P. Kaplieva,
Ya. A. Borovets,
O. A. Yarmolenko,
E. M. Jandarova,
A. D. Borsuk https://doi.org/10.51523/2708-6011.2025-22-2-14
Abstract
Objective. Demonstration of a clinical case of adrenal adenoma with mixed hormonal secretion.
Materials and methods. Retrospective analysis of the medical history of a patient who was hospitalized in the endocrinology department of the Republican Scientific and Practical Center for Radiation Medicine and Human Ecology.
Results. Endocrine arterial hypertension is a current problem of modern endocrinology. The majority of the arterial hypertension data is attributable to primary hyperaldosteronism, represented by adenoma or bilateral adrenal hyperplasia. Diagnosis of these conditions presents difficulties, requiring confirmation of the presence of a volumetric formation according to instrumental diagnostics, as well as laboratory confirmation of its hormonal activity. A clinician may find rare features indicating mixed hormonal secretion of benign adrenal lesions during the study,
Conclusion. Primary hyperaldosteronism and endogenous hypercortisolism are common causes of the development of secondary hypertension, which worsen patients’ quality of life and increase the risks of mortality and disability. The occurrence of adenomas with mixed secretion is extremely rare in endocrine practice, which does not affect the further management of patients, but poses special difficulties for diagnosis.
About the Authors
M. A. Duka
Gomel State Medical University
Belarus
Belarus
Maria A. Duka - Assistant at the Department of Internal Diseases No. 1 with courses of Endocrinology and Hematology, Gomel State Medical University.
Gomel
Ya. L. Naumenava
Gomel State Medical University; Republican Scientific and Practical Center for Radiation Medicine and Human Ecology
Belarus
Belarus
Yana L. Naumenava - Candidate of Medical Sciences, Associate Professor at the Department of Internal Diseases No. 1 with courses of Endocrinology and Hematology, Gomel State Medical University; Head of the Department of Endocrinology, Republican Scientific and Practical Center for Radiation Medicine and Human Ecology.
Gomel
M. P. Kaplieva
Gomel State Medical University
Belarus
Belarus
Marina P. Kaplieva - Candidate of Medical Sciences, Associate Professor, Associate Professor at the Department of Internal Diseases No. 1 with courses of Endocrinology and Hematology, Gomel State Medical University.
Gomel
Ya. A. Borovets
Republican Scientific and Practical Center for Radiation Medicine and Human Ecology
Belarus
Belarus
Yana A. Borovets - Endocrinologist, Department of Endocrinology, Republican Scientific and Practical Center for Radiation Medicine and Human Ecology.
Gomel
O. A. Yarmolenko
Gomel State Medical University
Belarus
Belarus
Olga A. Yarmolenko - Senior Lecturer at the Department of Internal Diseases No. 1 with courses of Endocrinology and Hematology, Gomel State Medical University.
Gomel
E. M. Jandarova
Gomel State Medical University
Belarus
Belarus
Elena M. Jandarova - Assistant at the Department of Internal Diseases No. 1 with courses of Endocrinology and Hematology, Gomel State Medical University.
Gomel
A. D. Borsuk
Republican Scientific and Practical Center for Radiation Medicine and Human Ecology
Belarus
Belarus
Alexey D. Borsuk - Head of the Endoscopy Department, Republican Scientific and Practical Center for Radiation Medicine and Human Ecology.
Gomel
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Review
For citations:
Duka M.A., Naumenava Ya.L., Kaplieva M.P., Borovets Ya.A., Yarmolenko O.A., Jandarova E.M., Borsuk A.D. Adrenal adenoma with mixed hormonal secretion. Health and Ecology Issues. 2025;22(2):121-125. (In Russ.) https://doi.org/10.51523/2708-6011.2025-22-2-14
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