THE COMPARATIVE ANALYSIS OF THE CLINICAL AND LABORATORY INDICATORS AND RHEOHEPATHOGRAPHY IN PATIENTS WITH MECHANICAL JAUNDICE, LIVER CIRRHOSIS, AND MULTIPLE ORGAN DYSFUNCTION SYNDROME

Abstract

Objective: to identify changes of indicators of tetrapolar rheohepathography (RHG) in patients with mechanical jaundice, liver cirrhosis, and multiple organ dysfunction syndrome (MODS) taking into account the comparative assessment of their clinical and laboratory indicators. Material and methods . The clinical and laboratory parameters and results of RHG were analyzed in 73 patients undergoing treatment from December 2015 to June 2017. Four groups were singled out: 1-st (control) - 27 patients with limb fractures, somatically practically healthy; 2-nd - 11 patients with mechanical jaundice; 3-rd - 14 patients with liver cirrhosis; 4-th - 21 patients with MODS. Results. It has been established that the parameters of RHG come back to normal within the first 24 hours after the surgical intervention to eliminate mechanical jaundice, despite the presence of an increased level of general bilirubin and cytolysis syndrome. The greatest degradation of the RHG parameters was diagnosed in the patients of the groups with liver cirrhosis and MODS. Conclusion. The parameters of RHG in patients with mechanical jaundice, liver cirrhosis, and MODS differ, which indicates different pathogenesis of the development of hepatic hemodynamics disorders in these conditions.