The systems medicaments analgesia occupy primary point in protection of surgical patient from pain. The analgesia have been achieved introduced analgesics different ways ensuring the bioavailability of them. Effects of analgesics developing after interaction of agonists to exciting or inhibition nociceptors in peripheral and central nerves structures. The therapeutic agents can interaction with neurotransmitters modality rise or cessation of the pain.

The present paper represents examination results of 210 women with dysplasia and cervical carcinoma. The rate of various papilloma viruses depending on severity of pathology is shown. For the diagnostics, the molecular-biological method of PCR with the use of multi-primer technology was applied. The paper analyses the incidence of human papilloma viruses of high and average cancerogenic risk in women with affected cervical epithelium of light and high degree, squamous cell cervical carcinoma.

Menopause at wоman starts at the age of 45-55. But it doesn’t mean complete stop of ovaries functioning. It is the reason of pregnancy after women’s period stop. Mostly the half of the pregnancies at women aged older than 40-45 are interrupted by abortion. The main aim of contraception at this group of women is prevention of abortion and its negative consequences.

30 women with tubo-peritoneal infertility were surveyed. Frequencies of chlamydia infections in the given group were investigated. Immunoassay, polymerase chain reaction were applied to diagnostics. Antibodies to Chlamydia trachomatis were determined at half of surveyed women. All patients underwent a medical - diagnostic laparoscopy, the degree of defeat fallopian tubes was estimated depending on size of a titer of antibodies to Chlamydia trachomatis.

We detect serum cytokines levels: tumor necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), interleukins (IL)-1 alpha (IL-1α) and IL-4 in 73 of patients with chronic hepatitis C (CHC). We registered increased cytokines’ levels: TNF-α (56.2%), IL-1α (50.7%), IFN-γ (15.1%) and IL-4 (12.3%). In patients with CHC the levels of all the cytokines were higher than in healthy blood donors (p<0.05). In 15.1% of CHC patients we revealed simultaneously increased levels of T helper 1 (Th1) cytokine (IFN-γ) and Th2 cytokines (IL-4 and/or IL-1α), that is indirect marker of cellular immune deficiency. In all the CHC patients we detected the antibody spectrum to different proteins of hepatitis C virus (HCV). We found the significantly higher levels of IFN-γ in those patients with antibodies to NS5 protein negative (p=0.022). There were no differences in cytokines levels depends on IgM antibodies to HCV in both positive and negative patients (p>0.05).

Аs a result of research the specific structure of the basic microorganisms in a wound at patients with pyoinflammatory diseases of skin and hypodermic adipose cellular tissue has been investigated. Sensitivity of the allocated microorganisms to the basic antibacterial preparations has been studied. Efficiency of use of a solution of neutral anolyte in complex treatment of patients with a surgical infection has been shown.

There were examined some experiments in the meanings in the area of postcholecystectomy syndrome. There were decided that some part of them is faced with mistakes of operating or iatrogenic injuries, others - with not full examination of patients or mistaken meaning of information. The main of diagnostics of biliary pathology after cholecystectomy is hepatic sonography, endoscopic retrograde cholangiopancreatography (ERCP), dynamic radionuclide hepatobiliary imaging. In the process during the examinations of papillary stenosis or choledocholithiasis were made endoscopic intervention. Biliary-enteric anastomosis was made to the patients with long papillary stenosis. The conservative cure was made by diagnostics of dynamic radionuclide hepatobiliary imaging of dysfunction Oddi's sphincter.

We, at Surgery Department, «Al-Nasr» Hospital, Ibb City, Yemen, studied the findings of using (the operation + chemical therapy) to treat 18 patients were suffering from (Echinococcosis). Operations were performed for them from 1999-2005.

It has been discovered that for chronic myeloleukosis and policythemia changes of a hemostasis are typical at those stage where directly participates platelet component, namely at the final stage of a blood clot formation and at a level of a platelet hemostasis. We demonstrate: on the background of normal or increased platelets level, saved based secondary hemostasis tests, the combination of hyperfibrinolysis, decrease in a clot volume, its density and a general hemostatic parameter results in functionally defective blood clot formation, which, in its turn, testifies about hemorrhagic risk.

Prognostic importance of leukocytic reaction for the acute renal failure (ARF) outcomes is evident. However, prognostic and information role of the leukogram during ARF is not still determined. Proposed leukogram analysis at different ARF periods in pediatric patients makes it possible to reveal negative illness tendency and to modify treatment.

Diseases of cardiovascular system rather frequently meet at the patients, suffering a pathology of a thyroid gland. However till now there are no data on concrete structurally functional changes of heart at various pathologies of thyroid gland. Morphological changes of capillaries and their direct cellular microenvironment, that is a vascular component of communication systems in fabrics of a thyroid gland are not detailed at her pathology. Research of capillaries and their direct cellular microenvironment in fabrics of a thyroid gland and a myocardium is represented perspective for specification of parts morphogenesis changes of a myocardium at various illnesses of thyroid gland.

Are submitted pathomorphological characteristics of vessels at presence of atherosclerotic changes in an aorta. In original research new approaches of a morphological estimation of fabric changes in a wall of an aorta which allow to give the objective characteristic morphogenetic processes at an atherosclerosis are offered.

Main aim of given study was comparison of effect of 20 mg/day of medostatin on level of lipids in different types of dyslipidemia - isoloted hypercholesterolemia and combined hyperlipidemia in patient with coronary heart disease. It was noted that 6 months therapy with medostatin exerted positive effect on blood lipid spectrum in both types of dyslipidemia.

The tuberculosis is the most serious infection at HIV-infection and often reason of their death. The overwhelming number of the patients with tuberculosis and HIV-infection lives in territory of the Gomel area. Among HIV-infection of the patients by a tuberculosis the quantity condemned, narcomaniacs, unemployeds very greater. The revealing of a tuberculosis at HIV-infection more often occurs at the manipulation in medical establishments to the complaints. The combination HIV-infection and tuberculosis is characterized by original current of disease with presence both pulmonary and внелегочных of defeats and tendency to generalization of process.

In the task are introduced the results of the first scheme of antiretroviral therapy «Timazid+ Hivid + Viracept» implementation by adults and children. Also is showed the inconvenience of the scheme using by bigger quantity of patients, its minimum toxicity, virological and immunological efficiency after 12 months

There was performed the analysis was done for treating the surgical complication of ascarisis on 71 patients who had undergone operations from 2002 to 2005 at Surgery Department, Al-Nasr Hospital, Ibb City, Yemen. In all operations, the patients were prescribed Albendazol for treating Round Worm.

The consecutive process of carboxyhemoglobin oxidation-reduction into oxihemoglobin was on study. The suggested model involves three main steps: carboxyhemoglobin oxidation into methemoglobin by hydroxyl radicals in aqueous medium generated by ultrasonic with frequency 880 Gt; methemoglobin reduction into deoxyhemoglobin by NaBH₄; deoxyhemoglobin oxidation into oxyhemoglobin by oxygen. The investigation revealed that proteins’ compartment in carboxyhemoglobin resists ultrasonic more efficiently than that of oxyhemoglobin.

It was established experimentally on rats that bacterial endotoxinemia of various origins, caused by pyrogenal injection and by CLP-peritonitis, was accompanied by disturbance of temperature homeostasis, activation of adrenal cortex and atherogenic changes in cholesterol content of blood lipoproteins: decrease of the amount of high density lipoprotein (HDL) cholesterol and increase of low and very low density lipoprotein (LDL and VLDL) cholesterol blood levels. Injection of exogenous glucocorticoid prednizolone during pyrogenal action prevents the decrease of the amount of HDL cholesterol but strengthens the increase of LDL and VLDL cholesterol blood levels. Activation of adrenal cortex at bacterial endotoxinemia is accompanied by inhibition of the negative feed-back mechanism in hypothalamic-pituitary-adrenal axis, what provides high activity of steroidogenesis during systemic inflammation.

Young people’s health is regarded as an integral part of the general system of social-ecological and ecological priorities in the governmental program of «People’s Health».

The review is devoted to the problems of identification and classification of probiotic strains of bifidobacteria that are widely used in manufacturing of medications and functional food products. It also discusses prospects of development of new probiotic products on the base of well-known commercial strains and possibilities of their wider use in different areas.

With blood loss of 50 ml a day there is no clinical signs, and blood presence in feces remains invisible. Losses like this are present in 80% of patients with gastroduodenal ulcers and, as a rule, present at complications. The cheapest and commonly used method of its detection is the occult blood feces analysis. The aim of the present investigation was to study the efficiency of different methods of occult blood feces analyses (hemoccult and immune-chemical occult blood feces analyses) as a screening method of the gastric cancer diagnostics. The investigation has revealed that hemoccult analysis is much more specific and sensitive than immune-chemical occult blood feces analysis in the diagnostics of the latent blood loss in patients with gastroduodenal ulcers which makes it more useful as a screening method to detect latent bleeding in upper regions of the GI tract.

The aim of this study was to evaluate the significance of enzyme-linked immunosorbent assay (EIA) and polymerase chain reaction (PCR) in diagnostics of hepatitis C virus (HCV-) infection. The sera samples from 500 of patients with acute and chronic forms of HCV-infection were tested by means of PCR and EIA (anti-HCV total and IgM in 35 of patients). PCR positive results were seen in 83% of patients and more often revealed in those patients with elevated ALT levels (χ² = 25.01; р = 0.0001). Both PCR and EIA positive results were in 81.8% of patients, both negative - in 0.4%. In 17.8% of cases results of PCR and EIA didn’t agree. In patients with anti-HCV IgM positive, HCV RNA were revealed more often than in those anti-HCV IgM negative (p = 0.009). Sensitivity of the anti-HCV IgM test in comparison with PCR was evaluated 51.9%, specificity - 100%. Detection of antibodies to HCV class IgM can be applied for an estimation of increased replicative activity of HCV. The use of both methods (EIA and PCR) allows improving HCV-infection diagnostics.

Acute renal failure (ARF) is a specific condition, which involves in the pathology multiple organs and systems of the human body, disturbing physiological parameters. Careful homeostatic monitoring is needed to reveal negative illness tendency and to modify treatment. However, a numerous blood testing in pediatric patients may be superfluous, that leads as to anemia progressing, as to treatment cost increasing. Proposed analysis of the prognostic and information importance of blood testing at pediatric patients demonstrates its unequal value at the different ARF periods. This fact makes possible to decrease a number of blood analysis and treatment cost.

In the help to practical doctors materials of own supervision viscerous forms of a deep mycosis - aspergillezis are resulted. Clinical and anatomic comparisons are lead, the example of construction of final clinical and pathoanatomical diagnoses is resulted.