Preview

Health and Ecology Issues

Advanced search

CLINICAL AND MORPHOLOGICAL ASPECTS OF GASTROPATHIES CAUSED BY TAKING NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

https://doi.org/10.51523/2708-6011.2009-6-3-17

Abstract

The results of examination, treatment and case monitoring of 19 patients, taking nonsteroidal anti-inflammatory drugs, consulted at the preventive gastroenterological center of the «Republican Research and Practical Center for Radiation Medicine and Human Ecology» because of metaplasia, dysplasia and hyperplasia on morphological research of biopsy material are presented. Сlinical and morphological manifestation of gastropathy, inducted by taking nonsteroidal anti-inflammatory drugs are analyzed.

About the Authors

E. N. Platoshkin
Gomel State Medical University
Belarus


N. V. Vasilevich
Gomel State Medical University
Belarus


References

1. Aspirin and risk of hemorrhagic stroke. A meta-analysis of controlled trials / H. J. Whelton [et al.] // JAMA. - 1998. - Vol. 280. - Р. 1930.

2. Gabriel, S. E. Risk for serious gastrointestinal complications related to use of nonsteroidal antiinflammatory drugs: a meta-analysis / S. E. Gabriel, L. Jaaklimainen, C. Bombadier // Ann Intern Med. - 1991. - Vol. 115. - Р. 787.

3. Vane, J. R. Inhibition of prostaglandin synthesis as a mechanisms of action for the aspirin-like drugs / J. R. Vane // Nature. - 1971. - Vol. 231. - Р. 232.

4. Аруин, Л. И. Морфологическая диагностика болезней желудка и кишечника / Л. И. Аруин, Л. Л. Капуллер, В. А. Исаков. - М.: Триада-Х, 1998. - 496 с.

5. Roth, S. H. NSAID gastropathy. A new understanding / S. H. Roth // Arch Intern Med. - 1996. - Vol. 156. - Р. 1623.


Review

For citations:


Platoshkin E.N., Vasilevich N.V. CLINICAL AND MORPHOLOGICAL ASPECTS OF GASTROPATHIES CAUSED BY TAKING NONSTEROIDAL ANTI-INFLAMMATORY DRUGS. Health and Ecology Issues. 2009;(3):76-80. (In Russ.) https://doi.org/10.51523/2708-6011.2009-6-3-17

Views: 236


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)