PROGNOSTIC SIGNIFICANCE OF EXPRESSION OF CYCLINES B1 AND D1 IN CASE OF OVARIAN CARCINOMA
https://doi.org/10.51523/2708-6011.2009-6-3-12
Abstract
Cyclins are a family of regulatory proteins that play a key role in controlling the cell cycle. Abnormalities of cell cycle regulators, including cyclins and cyclin dependent kinases, have been reported in various malignant tumors. Expression of cyclin B1, D1 was investigated with immunohistochemical method in 69 cases of primary ovarian carcinoma. Five-year survival and degree of differentiation have been found to depend on сyclins D1, В1.
About the Authors
A. V. Shulga
Grodno State Medical University
Belarus
Belarus
V. A. Basinski
Grodno Regional Clinical Hospital
Belarus
Belarus
S. E. Savicki
Grodno Regional Clinical Hospital
Belarus
Belarus
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Review
For citations:
Shulga A.V., Basinski V.A., Savicki S.E. PROGNOSTIC SIGNIFICANCE OF EXPRESSION OF CYCLINES B1 AND D1 IN CASE OF OVARIAN CARCINOMA. Health and Ecology Issues. 2009;(3):57-61. (In Russ.) https://doi.org/10.51523/2708-6011.2009-6-3-12
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