A GUAIAC PROBE AND AN IMMUNE MARKER TEST FOR HIDDEN BLOOD IN FAECES IN AN UNINVASIVE CANCER DIAGNOSTIC OF A GASTROINTESTINAL TRACT
https://doi.org/10.51523/2708-6011.2007-4-3-22
Abstract
The aim of an investigation was to study the diagnostic possibilities of various methods for revelation of hidden blood in faeces in an uninvasive cancer diagnostic of a gastrointestinal tract. The material and methods of the investigation: we have examined 43 patients diseased with a stomach cancer, 36 patients diseased with the gastro duodenal ulcers, 27 patients diseased with a stomach dyspepsia, 58 patients diseased with a colorectal cancer, 37 patients diseased with the bowels polyps, 57 patients diseased with a bowels stimulation syndrome and 26 healthy volunteers. Blood loss from a gastrointestinal tract determined by using the guaiac probe and immune marker test for hidden blood in faeces. The results of the investigation are: the immune marker test for hidden blood in faeces exceeds a hemoccult-test at a sensitiveness in revelation of the colorectal cancer (p < 0,05). It’s sensitiveness is quite high and makes up 93,8%. The hemoccult-test exceeds the immune marker test for hidden blood in faeces in revelation of the stomach cancer not only by the sensitiveness but a specific that is really important for the uninvasive test though in our investigation this tendency is not achieve a statistical meaning (p < 0,05). At that time according to our data the specific of the hemoccult-test in revelation of the stomach cancer is sufficiently high and makes 88,9%.
References
1. Global Cancer Statistics [electronic resource] / D. Max Parkin [et al.] // CA Cancer J. Clin. - 2005. - № 55.- Р. 74-108.
2. Портной, Л. Лучевая диагностика «современного» рака желудка (конспект врача) [Электронный ресурс] / Л. Портной, О. Вятчанин // Медицинская газета. - 2005. - № 44. - Режим доступа: http://zhuravlev.info/modules.php?file=article&name=News&sid=180. - Дата доступа: 25.07 2007.
3. Российское противораковое общество. Скрининг рака желудка [электронный ресурс]. - М., 2007. - Режим доступа: http://www.pror.ru/screening_stomach. shtml. - Дата доступа: 21.07.2007
4. Randomised study of screening for colorectal cancer with faecaloccult-blood test / J.S. Mandel [et al.] // Lancet. - 1996. - Vol. 348, № 9040. - Р. 1467-1471.
5. Population based surveillance by colonoscopy: effect on the incidence of colorectal cancer / Е. Thiis-Evensen [et al.] // Scand. J. Gastroenterol. - 1999. - № 34. - Р. 414-420.
6. Михайлова, Е. И. Скрининг колоректального рака (литературный обзор) / Е. И. Михайлова // Проблемы здоровья и экологии. - 2005. - № 2. - Р. 79-82.
7. Реброва, О. Ю. Статистический анализ медицинских данных / О. Ю. Реброва. - М.: Медиа Сфера, 2006. - 305 с.
8. St. John, D.S.B. Stool occult blood testing for colorectal cancer: a critical analysis / D.S.B. St. John, G. P. Young // Practical Gastroenterology. - 1992. - № 8. - P. 19-23.
9. Repeated screening for colorectal cancer with fecal occult blood test / O. Kronborg [et al.] // Scand. J. Gastroenterol. - 1989. - № 24. - P. 599-606.
10. Randomized, controlled trial of faecal occult blood screening for colorectal cancer: results for the first 107,349 subjects / J. D. Hardcastle [et al.] // Lancet. - 1989. - № 1. - P. 1160-1164.
11. Screening and rescreening for colorectal cancer: a controlled trial of fecal occult blood testing in 27,700 subjects / J. Kewenter [et al.] // Cancer. - 1988. - Vol. 62. - P. 645-651.
Review
For citations:
Michailova E.I. A GUAIAC PROBE AND AN IMMUNE MARKER TEST FOR HIDDEN BLOOD IN FAECES IN AN UNINVASIVE CANCER DIAGNOSTIC OF A GASTROINTESTINAL TRACT. Health and Ecology Issues. 2007;(3):128-134. (In Russ.) https://doi.org/10.51523/2708-6011.2007-4-3-22
Views: 309
Email this article 