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FACTORS OF PROGNOSIS OF THE CANCER OF RECTUM II-III STADIUM AFTER PREOPERATIVE RADIATION THERAPY

https://doi.org/10.51523/2708-6011.2007-4-3-9

Abstract

We researched factors of prognosis of the cancer of rectum 2-3 stadium after preoperative radiation therapy. Correlative dependencies between apart prognostic rates which characterize complications of the main disease (development of recidives, production of metastasis) were estimated. Prognostic importance in quality of factors, negatively influencing on the prognosis of the disease was revealed. Tumor size, kind of growth and invasive growth into intestinal wall, quantity of lymphatic nodes with metastasis, high level of Ki-67, p53 expression, stage of malignancy, conditions of tumor edge and intravascular invasion occurred to be the most important. The results, we got, can be used in evaluation of the stage of risk of postoperative complications development after carried preoperative radiation therapy.

About the Authors

S. L. Achinovich
Gomel Regional Clinical Oncologycal Dispancer
Belarus


E. A. Nadierov
Gomel State Medical University
Belarus


O. A. Golubev
Gomel State Medical University
Belarus


References

1. Залуцкий, И. В. Алгоритмы диагностики и лечения злокачественных новообразований / И. В. Залуцкий, Э.А. Жаврида. - Мн.,2007. - С. 128-136.

2. Эпидемиология злокачественных новообразований в Беларуси / И. В. Залуцкий и [др.]. - Мн.: Зорны верасень, 2006. - С. 59-68.

3. Пальцев, М. А. Атлас патологии опухолей человека / М. А. Пальцев, Н. М. Аничков. - М.:ОАО «Медицина», 2005. - С. 213-223.

4. Поляков, С. М. Злокачественные новообразования в Беларуси 1996-2005 / С. М. Поляков, Л. Ф. Левин. - Мн.: БЕЛЦМТ, 2006. - С. 58-60.

5. Expression of p53 in Colorectal Carcinoma: Correlation with сlinicopathologic Features / M. R. Ghavam-Nasiri [et al.] // Arch.Iran.Med. - 2007. - Vol. 10 (1). - P. 38-42.

6. Jurach, M. T. Expression of the p53 protein and clinical and pathologic correlation in adenocarcinoma of the rectum / M. T. Jurach, L. Meurer, L. F. Moreira // Arq. Gastroenterol. - 2006. - Vol. 43(1). - P. 9-14.

7. Adenocarcinoma of the rectum with various grades of atipia in association with Crohn s disease: a case report and immunohistochemistry of p53 and Ki-67 / K. Koda [et al.] // Pathol. Int. - 2000. - Vol. 50(4). - P. 318-326.

8. Pereira, T. Jr. Lymph node evaluation in colorectal cancer / T. Jr., Pereira, R. A. Torres, A. M. Nogueira // Arq.Gastroenterol. - 2006. - Vol. 43(2). - P. 89-93.

9. Prognostic importance of isolated peritumoral lymphangiosis carcinomatosa in lymph-node-negative colorectal carcinoma / W. Meyer [et al.] // Langenbecks Arch. Surg. - 2001. - Vol. 326(2). - P. 124-131.

10. Choi, H. J. Incidence and prognostic implications of isolated tumor cells in lymph nodes from patients with Dukes B colorectal carcinoma / H. J. Choi, Y. Y. Choi, S. H. Hong // Dis. Colon Rectum. - 2002. - Vol. 45(6). - P. 750-756.

11. Jass, J. R. Reporting colorectal cancer / J. R. Jass, B. C. Morson // J. Clin. Pathol. - 1987. - Vol. 40. - P. 1016-1023.

12. Seifart, W. Prognostic significance of cellular stromal reaction at the tumor margin and the reaction in the regional lymph nodes in rectal adenocarcinoma. Patient follow-up studies after curative abdominoperineal rectal amputation / W. Seifart, G. P. Wildner // Arch. Geschwulstforsch. - 1983. - Vol. 53(6). - P. 579-588.

13. Change in location of colorectal cancer in Hungarian patients between 1993-2004 / P. Fuszek [et al.] // Orv. Hetil. - 2006. - Vol. 147(16). - P. 741-746.

14. Relation between stage,grade,proliferation,and expression of p53 and CD 44 in adenomas and carcinomas of the colorectum / P. A. Jackson [et al.] // J. Clin. Pathol. - 1995. - Vol. 48. - P. 1098-1101.

15. Thomschke, D. Local recurrence and survival rate after rectal cancer operations and multimodal therapy / D. Thomschke, B. Kyau-Ummen, H. J. Halbfass // Chirurg. - 2002. - Vol. 73(3). - P. 245-254.


Review

For citations:


Achinovich S.L., Nadierov E.A., Golubev O.A. FACTORS OF PROGNOSIS OF THE CANCER OF RECTUM II-III STADIUM AFTER PREOPERATIVE RADIATION THERAPY. Health and Ecology Issues. 2007;(3):49-54. (In Russ.) https://doi.org/10.51523/2708-6011.2007-4-3-9

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ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)