ASSESSMENT OF PROGNOSTIC VALUE OF SMOOTH MUSCLE ACTIN EXPRESSIONS IN PROSTATE CANCER
https://doi.org/10.51523/2708-6011.2007-4-2-17
Abstract
Based оn the data yielded by immunohistochemical and morphometric research, expressions of smooth muscle actin in the prostate cancer were analysed. It was revealed, that its low expression in a stroma of neoplasms and in walls of vessels is more characteristic of low-grade cancers and tumours with higher metastatic potential. In addition, low-grade cancers featured disturbance of the formation of vessels’ smooth muscle skeleton, decrease of its thickness, appearance of discontinuity and defects of smooth muscle layer, which reflect imperfection of neoangiogenesis and can be a prognostic marker of a neoplasm.
About the Authors
A. K. Grib
Grodno State Medical University
Belarus
Belarus
V. A. Basinskii
Grodno State Medical University
Belarus
Belarus
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Review
For citations:
Grib A.K., Basinskii V.A. ASSESSMENT OF PROGNOSTIC VALUE OF SMOOTH MUSCLE ACTIN EXPRESSIONS IN PROSTATE CANCER. Health and Ecology Issues. 2007;(2):106-110. (In Russ.) https://doi.org/10.51523/2708-6011.2007-4-2-17
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