THE PECULIARITIES OF GHRELIN BASAL SECRETION AT PATIENTS WITH METABOLIC SYNDROME

To estimate the peculiarities of ghrelin basal secretion there were examined patients aged 35-55 with metabolic syndrome manifestations (n = 96) and practically healthy (n = 26). There was established that ghrelin levels in the main group were authentically lower than in the control one and were reducing as there was the increase of manifestation degree of carbohydrate metabolism disorder. At correlation analysis with the main MS components there was revealed the negative connection with anthropometric parameters - Body Weight Index , Waist Circumference, Waist Circumference / Hips Circumference, systolic blood pressure and diastolic blood pressure and indexes IR - HOMA-IR and positive with Reciprocal of НОМА-R.

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