ANTIOXIDATIVE ACTIVITY OF BILE AT PATIENTS WITH ACUTE CHOLANGIOGENIC THE INFECTION
https://doi.org/10.51523/2708-6011.2007-4-1-10
Abstract
It is investigated antioxidative activity of bile at various categories of patients with acute cholangiogenic an infection. The used technique for the first time is offered for research of bile. It is revealed, that in norm bile possesses antioxidative activity. At obstruc bilious channels and development of their inflammation there is an exhaustion antioxidative properties of bile and substantial growth in it of quantity of the substances possessing prooxidative activity. Originally, the increase prooxidative activity of bile is caused by a bilious hypertensia and a mechanical jaundice. In process of progressing destructive processes in bilious ways prooxidative activity of bile accrues and is accompanied by the expressed insufficiency antioxidative protection. Dynamics peroxidative the processes registered in bile, reflects not only presence of pathological process, but also weight, and depth of defeat.
About the Authors
A. A. Al-FidyBelarus
A. I. Gritsuk
Belarus
Z. A. Dundarov
Belarus
References
1. Davies, K. J. Oxidative stress: The paradox of aerobic life / K. J. Davies // Biochem. Soc. Symp. - 1995. - Vol. 61. - P. 1-31.
2. Davies, K. J. Oxigen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes / K. J. Davies, A. L. Goldberg // J. Biol. Chem. - 1998. - Vol. 262. - P. 8220-8226.
3. Василькова, Т. В. Активность мембраносвязанных ферментов и антиоксидантная защита от липопереокисления в эритроцитах при гипотермии: дис. … канд. мед. наук: 03.00.04. / Т. В. Василькова. - Мн., 1998. - 120 с.
4. Колб, В. Г. Лабораторная диагностика хирургических заболеваний: справочное пособие / В. Г. Колб, В. С. Камышников. - Мн. : Выш. шк., 1993. - 185 с.
5. Сирота, Т. В. Новый подход в исследовании процесса аутоокисления адреналина и использование его для измерения активности супероксиддисмутазы / Т. В. Сирота // Вопр. мед. химии. - 1999. - Т. 45, № 3. - С. 263-272.
6. Оценка состояния антиоксидантной активности слезной жидкости / А. И. Грицук [и др.] // Биомедицинская химия. - 2006. - Т. 52, Вып. 6. - С. 601-607.
Review
For citations:
Al-Fidy A.A., Gritsuk A.I., Dundarov Z.A. ANTIOXIDATIVE ACTIVITY OF BILE AT PATIENTS WITH ACUTE CHOLANGIOGENIC THE INFECTION. Health and Ecology Issues. 2007;(1):52-56. (In Russ.) https://doi.org/10.51523/2708-6011.2007-4-1-10