PECULIARITIES OF POIKILOCYTOSIS INDUCED BY REACTIVE NITROGEN SPECIES ACTION
https://doi.org/10.51523/2708-6011.2006-3-2-23
Abstract
The changes in a shape, a structure and mechanical properties of erythrocyte membrane after the treatment of whole human blood with peroxynitrite were studied by the methods of light, electron scanning and atomic force microscopy. The primary mechanisms of the changes in erythrocyte shape (acanthocytosis and spherocytosis) at the action of reactive nitrogen species state to be lipid phase separation as a result of lipid peroxidation and spectrin aggregation.
About the Authors
M. N. Starodubtseva
Gomel State Medical University
Belarus
Belarus
T. G. Kuznetsova
Gomel State Medical University
Belarus
Belarus
T. A. Kuznetsova
Institute Heat-and-mass Transfer of NAS of Belarus of a name A.V. Likov
Belarus
Belarus
J. C. Ellory
Oxonian University
Belarus
Belarus
S. N. Cherenkevich
Belarussian State Medical University
Belarus
Belarus
S. O. Abetkovskaya
Belarussian State Medical University
Belarus
Belarus
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Review
For citations:
Starodubtseva M.N., Kuznetsova T.G., Kuznetsova T.A., Ellory J.C., Cherenkevich S.N., Abetkovskaya S.O. PECULIARITIES OF POIKILOCYTOSIS INDUCED BY REACTIVE NITROGEN SPECIES ACTION. Health and Ecology Issues. 2006;(2):117-121. (In Russ.) https://doi.org/10.51523/2708-6011.2006-3-2-23
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