GLUCOCORTICOID FUNCTION DISORDERS OF ADRENAL GLANDS CORTEX UNDER PANCREAS HEAD CANCER COMPLICATED BY OBSTRUCTIVE JAUNDICE

Abstract

There was studied the function of adrenal glands cortex at 89 patients with pancreas head cancer complicated by obstructive jaundice through cortisol level definition in blood before and after operation. There was performed cholecystojejunoanastomosis with interintestinal fistula from standard laparotomy approaches for control group patients (46 persons). In basic group (43 persons) there was provided choledochoduodenal anastomosis from minilaparotomy approach. It was marked the significant decrease of glucocorticoids level in blood in pre-surgical period. It was revealed that the operations from the minilaparotomy approach performed at such patients provide less negative impact on adrenal glands activity than operations provided from traditional approaches. It decreases the risk of heavy post operative complications.