Relationship between pelvic organ prolapse and chronic pelvic pain in women
https://doi.org/10.51523/2708-6011.2026-23-2-01
Abstract
Objective. To study clinical and pathophysiological relationship between pelvic organ prolapse (POP) and chronic pelvic pain syndrome (CPPS) in women, to identify pain development mechanisms, and to consider diagnostic and treatment tactics.
Materials and methods. Scientific publications for the past 10 years, clinical guidelines, and epidemiological data on POP and CPPS were analyzed for a given time frame. Pathophysiological mechanisms (nociceptive, neuropathic pain, central sensitization), POP-Q classification, diagnostic methods (ultrasound, MRI, urodynamics) were studied.
Results. Multifactorial POP-CPPS relationship was identified: chronic pain through mechanical (fascia stretching), compressive (nerve compression), neuroinflammatory mechanisms develop in 30-50% of women with prolapse. Kegel exercises and pessaries are effective in treating this condition, as well as the use of antidepressants (duloxetine, vortioxetine) when CPPS is combined with depressive disorders.
Conclusion. A multidisciplinary, personalized approach is required in the treatment of these conditions. Antidepressants are shown to be effective in treating central sensitization and psychoemotional disturbances accompanying CPPS in POP.
About the Author
I. A. Korbut
Gomel State Medical University
Belarus
Belarus
Irina A. Korbut, Candidate of Medical Sciences, Associate Professor, Associate Professor at the Department of Obstetrics and Gynecology with the course of Advanced Training and Retraining
Gomel
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Review
For citations:
Korbut I.A. Relationship between pelvic organ prolapse and chronic pelvic pain in women. Health and Ecology Issues. 2026;23(2):7-14. (In Russ.) https://doi.org/10.51523/2708-6011.2026-23-2-01
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