Experience of biospecific hemosorbtion by using «Hemoproteazosorb» sorbent in patients with acute pancreatitis
https://doi.org/10.51523/2708-6011.2024-21-4-16
Abstract
Objective. To provide a clinical assessment of the effectiveness of biospecific hemosorption using the sorbent “Hemoproteazosorb” in patients with severe acute pancreatitis; to substantiate the importance of this method in a comprehensive approach to the treatment of the disease.
Materials and methods. The analyses of clinical cases of 61 patients with acute pancreatitis over 2023, whose therapy was supplemented with biospecific hemosorption and other methods of extracorporeal detoxification, was conducted. Clinical aspects of the disease, the results of laboratory and instrumental research methods, as well as the survival, mortality indices and subsequent development of complications were compared.
Results. The analyses of obtained data demonstrated efficacy of the sorbtion method in initial stages of the disease treatment, patients’ survival growth and time shortening of stay in the anesthesiology, resuscitation and intensive care department, and a decrease in the percentage of development of purulent-septic complications in future.
Conclusion. Biospecific hemosorbtion with the sorbent «Hemoproteazosorb» in acute pancreatitis as a part of a comprehensive treatment approach has proven to be an effective therapy method that significantly improves patients’ chances of a favorable outcome.
Keywords
acute pancreatitis,
acute destructive pancreatitis,
inflammation of the pancreas,
hemoperfusion,
sorbtion
detoxication,
hemosorbtion
Supporting agencies: The article was conducted without sponsorship.
About the Authors
H. A. Shautsova
Gomel City Clinical Emergency Hospital
Belarus
Belarus
Halina A. Shautsova, Anesthesiologist-Resuscitator at the Department of Extracorporeal Methods of Detoxification and Hyperbaric Oxygenation
Gomel
A. A. Shypulia
Gomel City Clinical Emergency Hospital
Belarus
Belarus
Aliaksandr A. Shypulia, Board Certified AnesthesiologistResuscitator at the Department of Extracorporeal Methods of Detoxification and Hyperbaric Oxygenation
Gomel
A. V. Denisenko
Gomel City Clinical Emergency Hospital
Belarus
Belarus
Andrei V. Denisenko, Anesthesiologist-Resuscitator at the Department of Extracorporeal Methods of Detoxification and Hyperbaric Oxygenation
Gomel
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For citations:
Shautsova H.A., Shypulia A.A., Denisenko A.V. Experience of biospecific hemosorbtion by using «Hemoproteazosorb» sorbent in patients with acute pancreatitis. Health and Ecology Issues. 2024;21(4):149-155. (In Russ.) https://doi.org/10.51523/2708-6011.2024-21-4-16
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