Atypical clinical case of ankylosing spondylitis
https://doi.org/10.51523/2708-6011.2025-22-1-16
Abstract
Objective. To demonstrate a clinical case of atypical ankylosing spondylitis.
Materials and methods. Retrospective analysis of the medical history of a patient hospitalized in the Rheumatology Department of Gomel City Clinical Hospital No. 1.
Results. Ankylosing spondylitis is one of the most difficult to diagnose causes of specific pain in the lower back. The medical and social significance of the disease lies in a high level of disability of young people, and in a decrease in the quality of patients’ life. There are no specific diagnostic markers of spondylitis at an early stage of the disease. The reasons for the late diagnosis of the disease are the untimely arrival of patients for medical help, the asymptomatic course of ankylosing spondylitis, and insufficient knowledge of the diagnostic criteria of the disease by doctors.
The article presents a clinical case of atypical ankylosing spondylitis in a young patient with no signs of systemic inflammation and classic manifestations of the disease.
Conclusion. Targeted examination of the lumbosacral spine and sacroiliac joints should be recommended for patients with pain in the lower back in order to verify ankylosing spondylitis.
About the Authors
A. E. KarpenkaBelarus
Alena E. Karpenka - Assistant at the Department of Internal Medicine No. 1 with the courses of Endocrinology and Hematology.
Gomel
E. M. Jandarova
Belarus
Elena M. Jandarova - Assistant at the Department of Internal Medicine No. 1 with the courses of Endocrinology and Hematology.
Gomel
E. G. Malaeva
Belarus
Ekaterina G. Malaeva - Candidate of Medical Sciences, Associate Professor, Head of the Department of Internal Diseases No.1 with the courses of Endocrinology and Hematology, Gomel SMU.
Gomel
A. N. Tsyrulnikova
Belarus
Anna N. Tsyrulnikova - Senior Lecturer at the Department of Internal Diseases No. 1 with the courses in Endocrinology and Hematology.
Gomel
E. V. Shulkina
Belarus
Elena V. Shulkina - Clinical laboratory diagnostics doctor (Head).
Gomel
K. S. Kravets
Belarus
Karina S. Kravets - Radiologist at the Department of Diagnostic Radiology.
Gomel
M. P. Bychenko
Belarus
Marina P. Bychenko - Neurologist at the Neurological Department for Stroke Patients.
Gomel
References
1. Filatova ES, Erdes SF. Features of chronic pain syndrome in patients with ankylosing spondylitis. Therapy. 2018;(7-8):82-88. (In Russ.). DOI: https://doi.org/10.18565/therapy.2018.7-8.82-88
2. Nurgaliev KJ, Isaeva BG. Ankylosing spondylitis, early diagnosis of intestinal lesions. Medicine (Almaty). 2019;203(5):75-79. (In Russ.). DOI: https://doi.org/10.31082/1728-452X-2019-203-5-75-79
3. Puedmag RD. Changing the quality of life of patients with ankylosing spondylitis on the background of basic therapy. In: Youth science and modernity: Proceedings of the 85th International Scientific Conference of Students and Young Scientists dedicated to the 85th anniversary of KSMU; 2020, April 23–24; Kursk. Kursk: Kursk State Medical University; 2020;1:631-633. (In Russ.).
4. Sklyarov BA, Pavlov BV. The study of genetic factors influencing the occurrence of Bekhterev’s disease (ankylosing spondylitis) in the Russian population. International Journal of Humanities and Natural Sciences. 2023;6-2(81):83-86. (In Russ.). DOI: https://doi.org/10.24412/2500-1000-2023-6-2-83-86
5. Erdes SF, Sakharova KV. Clinical picture of ankylosing spondylitis in HLA-B27 positive and negative patients. Modern rheumatology. 2023;17(5):61-66. (In Russ.). DOI: https://doi.org/10.14412/1996-7012-2023-5-61-66
6. Kireev VV, Suyarov AA, Khatamov HM, Mutalov BB. Immunological changes in ankylosing spondylitis. Journal of Theoretical and Clinical Medicine. 2022;(3):50-52. (In Russ.).
7. Martynova IA, Koryakin AM, Misyura EA, Kovalenko VM. The prevalence of clinical symptoms in patients with ankylosing spondylitis in the rheumatology department. Medicine in Kuzbass. 2019;18(3):80-84. (In Russ.).
8. Saidrasulova GB, Mukhammadieva SM, Khuzhaev RB, Ruzikulova S. Features of early clinical manifestations of ankylosing spondylitis. In: Botkin readings: сollection of abstracts of the All-Russian Congress; 2018, May 21-22; St. Petersburg. St. Petersburg: St. Petersburg Public Organization “Man and his Health”, 2018. pp. 336-337. (In Russ.).
9. Bunchuk NV, Levshakova AV. Tips for the diagnosis of ankylosing spondylitis/axial spondylitis. Consilium Medicum. 2023;25(11):755-765. (In Russ.). DOI: https://doi.org/10.26442/20751753.2023.11.202461
10. Murzabaeva MD. The effectiveness of golimumab in the treatment of ankylosing spondylitis and rheumatoid arthritis (own experience). Medicine (Almaty). 2020; 215-216(5-6):24-31. (In Russ.). DOI: https://doi.org/10.31082/1728-452X-2020-215-216-5-6-24-31
11. Volchenko DV, Akhtyamov IF, Terskov AYu. Short-term results of total hip replacement in patients with ankylosing spondylitis (primary message). The genius of orthopedics. 2021;27(1):38-42. (In Russ.). DOI: https://doi.org/10.18019/1028-4427-2021-27-1-38-42
12. Kulembayeva AB, Brimzhanova MD, Esirkepova GS, Fayzullina KM. Unified information system in rheumatology of the Republic of Kazakhstan: the status of the register of patients with rheumatoid arthritis and ankylosing spondylitis. Bulletin of the Kazakh National Medical University. 2018;(2):464-466. (In Russ.).
13. Sivordova LE, Polyakova YuV, Hakhverdyan YuR, et al. Secondary osteoporosis on the background of idiopathic ankylosing spondylitis: epidemiology, pathogenetic mechanisms and therapeutic possibilities of alfakalcidol. In: Botkin readings: All-Russian Scientific and Practical Conference: collection of abstracts; 2017, May 11-12; St. Petersburg. St. Petersburg: St. Petersburg Public Organization “Man and his Health”, 2017. pp. 235-236. (In Russ.).
14. Simonova OV, Sukhoi EN, Smirnova LA, Timin MV. A clinical case of successful kidney transplantation in a patient with secondary amyloidosis on the background of ankylosing spondylitis. The attending physician. 2020;(1):36-38. (In Russ.). DOI: https://doi.org/10.26295/OS.2019.90.42.007
15. Vysogortseva ON, Usmankhodzhaeva AA, Mavlyanova ZF. The use of NUGA BEST rehabilitation equipment in a comprehensive program of rehabilitation treatment of patients with ankylosing spondylitis. Sports medicine: science and practice. 2020;10(1):13-20. (In Russ.). DOI https://doi.org/10.17238/ISSN2223-2524.2020.1.13
16. Erdes SF. Recent achievements and prospects for the treatment of axial spondyloarthritis/ankylosing spondylitis. Modern rheumatology. 2021;15(2):94-105. (In Russ.). DOI: https://doi.org/10.14412/1996-7012-2021-2-94-105
17. Makarov VV, Tsyrenov AB, Vetchinova NV, Lizander OA. The role of physical therapy in ankylosing spondylitis (Bekhterev’s disease). In: Research by young scientists: proceedings of the III International Scientific Conference; 2019, October 20-23; Kazan. Kazan: Young Scientist, 2019. pp. 52-56. (In Russ.).
18. Al-Zamil M.H. Effectiveness of ultrasound therapy and phonophoresis in the treatment of ankylosing spondylitis. Clinical Neurology. 2021;(4):14-18. (In Russ.).
19. Vishnevsky AA. Surgical treatment of patients with ankylosing spondylitis in Andersen syndrome. In: I International Congress of the Association of Rheumatopoeologists: Abstracts of the Congress; 2017, September 28-29; Moscow. Moscow: Publishing and Printing Center “Scientific Book”, 2017. pp. 11-12. (In Russ.).
Review
For citations:
Karpenka A.E., Jandarova E.M., Malaeva E.G., Tsyrulnikova A.N., Shulkina E.V., Kravets K.S., Bychenko M.P. Atypical clinical case of ankylosing spondylitis. Health and Ecology Issues. 2025;22(1):127-136. (In Russ.) https://doi.org/10.51523/2708-6011.2025-22-1-16