Changes in the gut microbiome in children with atopic dermatitis
https://doi.org/10.51523/2708-6011.2024-21-3-05
Abstract
Objective. To determine the peculiarities of species composition and quantitative ratios of microorganisms in the intestine of patients with atopic dermatitis.
Materials and methods. Fecal microbiologic examination was carried out in 50 children with atopic dermatitis aged from 1 to 17 years to determine the species composition and quantitative ratios of microorganisms in the intestine.
Results. The change in the species composition and quantitative ratios of microorganisms in the intestine was detected in 84% of children with atopic dermatitis. Decreases in the number of lactobacilli and/or bifidobacteria were observed in half of the patients, changes in the qualitative and quantitative composition of Escherichia coli were detected in 50% of children with atopic dermatitis. The I severity level of intestinal dysbiosis was detected in 5 (10%) patients with atopic dermatitis, II level - in 16 (32%) patients, III level - in 21 (42%) children.
Conclusion. In children suffering from atopic dermatitis the frequent occurrence of intestinal dysbiosis was revealed mainly due to the decrease of the main representatives of the obligate intestinal microflora, bifido- and lactobacilli, as well as due to changes in the qualitative and quantitative composition of Escherichia coli.
About the Authors
L. A. Paroshyna
Gomel State Medical University
Belarus
Belarus
Larysa A. Paroshyna, Senior Lecturer at the Department of Internal Medicine №2,
Gomel
Sadchenko P. S.
Gomel State Medical University
Belarus
Belarus
Polina S. Sadchenko, Student,
Gomel
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Review
For citations:
Paroshyna L.A., S. S.P. Changes in the gut microbiome in children with atopic dermatitis. Health and Ecology Issues. 2024;21(3):40-44. (In Russ.) https://doi.org/10.51523/2708-6011.2024-21-3-05
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