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INFLUENCE OF MELANIN ON THE INDUCTION OF MICRONUCLEI AND APOPTOSIS AFTER RADIATION INFLUENCE

https://doi.org/10.51523/2708-6011.2004-1-2-4

Abstract

The influence of melanin pigment on micronuclei frequency and «genetic» apoptosis induction in human peripheral blood lymphocytes after low dose radiation exposure has been studied. Melanin is known to be natural substance with shown radioprotective activity. Results of the investigation revealed that melanin has no cytotoxic effect and its addition to the cell medium one hour before irradiation was accompanied by decrease of micronuclei frequency and apoptosis level in irradiatd lymphocytes, thus showing radioprotective effect.

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Review

For citations:


Melnov S., Marozik P., Melnova N. INFLUENCE OF MELANIN ON THE INDUCTION OF MICRONUCLEI AND APOPTOSIS AFTER RADIATION INFLUENCE. Health and Ecology Issues. 2004;(2):28-34. (In Russ.) https://doi.org/10.51523/2708-6011.2004-1-2-4

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ISSN 2708-6011 (Online)