MEDICAL AID AND RESEARCH PROJECTS FROM NAGASAKI ON RADIATION HEALTH EFFECTS AROUND CHERNOBYL
https://doi.org/10.51523/2708-6011.2004-1-1-1
Аннотация
The medical cooperative projects from Nagasaki to the former USSR have been performed in mainly two regions: Chernobyl and Semipalatinsk since 1990 and 1995, respectively. What we should do here in Nagasaki and also from Nagasaki will be discussed at the standpoint of humanitarian medical aid and scientific research collaboration usinsgt different channels of governmental and non-governmental cooperative linkages. The 21st Center of Excellence (COE) program of «International Consortium for Medical Care of Hibakusha and Radiation Life Science» established in Nagasaki University can serve our knowledge and experience much more directly in relation to the radiocontaminated areas in the world, and indeed contribute to the lessons learned from Chernobyl and also to the newly establishme of Network of Excellence (NOE) for Radiation Emergency Medicine under the auspices of the WHO-REMPAN. Within the frame of the International Consortium of Radiation Research, a molecular epidemiology of thyroid diseases has now been conducted in our departments. The clue of radiation-associated thyroid carcinogenesis may give us a new concept on experimental and epidemiological approaches to low dose radiation effects on human health, including internal radiation exposure.
Об авторе
Shunichi YamashitaЯпония
Список литературы
1. Thompson D.E., et al. Cancer incidence
2. inatomic bomb survivors. Part II: Solid
3. tumors 1958—1987. RadiaRes 1994; 137: S17
4. —S67.
5. Yamashita Si, Shibata Y., Namba H.,
6. Takamura N., Saenko V. Molecular
7. epidemiology of childhood thyroid cancer
8. around Chernobyl. Radiation and Homeostasis.
9. eds by Sugawara T, Nikaido 0, Niwa 0.
10. Excerpta Medica 2002; ICS
11. ; p201— p205.
12. Yamashita S., Shibata Y. (eds)
13. Chernobyl;A Decade. Excerpta Medica 1997; ICS
14. ; p 613.
15. Yamashita S, Shibata Y., Hoshi M, Fujimura
16. К(eds) Chernobyl; Message for the 21st
17. Century.Excerpta Medica 2002; ICS 1234;
18. p354.
19. Takamura N., Kryshenko N.,
20. Masyakin V.,Tamashiro H., Yamashita S.
21. Chernobyl-induced radiophobia and the
22. incidence of tuberculosis.Lancet 2000;
23. : 257.
24. Shibata Г., Yamashita S.,
25. Masyakin V.,Nagataki S. Fifteen years
26. after the Chernobyl ac cident, novel
27. evidence of post-Chernobyl thyroid
28. cancer. Lancet 2001; 9297: 1965—1966.
29. Fofanova O., Takamura N., Kinoshita K,
30. VorontsovA, Vladimirova V., DedovII., Peterkova
31. V.A.,Yamashita S. MR imaging of th pituitary
32. gland in children with congrenital combined
33. pituitary hormone deficiency associated with
34. PROP1 mutations.Am J Roentogenol 2000;
35. :555—559.
36. Alipov G., Takamura N., ho M., Pulgro
37. E.,Yamashita S. Ret/PTC rearrangement in
38. thyroid
39. cancer around Semipalatinsk nuclear testing
40. sites. Lancet 1999; 354: 1528—1529.
41. Hamada A., Takamura N.. Meirmanov
42. S.,Alipov G., Mine M., Ensebaev R.,
43. Sagandikova S.,Ohashi Т., Yamashita S. No
44. evidence of radiation risk for thyroid gland
45. among schoolchildren around Semipalatinsk
46. nuclear testing site. Endocrine J 2003; 50: 85—
47.
48. S-Yoshida Y., Sugiyama . Rogounovitch
49. T,Ohtsuru A., Namba H., Saenko V.,
50. Yamashita S.Radiation-inducible hSNK gene is
51. transcription-ally regulated by p53 binding
52. homology element in human thyroid cells.
53. Biochem Biophys Res Commun 2001; 289:
54. —498.
55. Mitsutake N., Namba Я, Shklyaev S.,
56. Tsukazaki Т., Ohtsuru A., OhbaM., Kuroki Т.,
57. Ayabe H.,Yamashita S. PKC delta mediates
58. ionizing radiation-induced activation of c-Jun
59. NH2-terminal kinase through MKK7 in
60. human thyroid cells.
61. Oncogene 2001; 20: 989—996.
62. Ishigaki K., Namba H., Nakashima
63. M.,Nakayama 7'., Mitsutake N., Hayashi Т.,
64. Maeda S.,IchinoseM., Kanematsu T, Yamashita
65. S. Aberrant localization of beta-Catenin
66. correlates with over-expression of its target
67. gene in human papillary thyroid cancer. J
68. Clin Endocrinol Metab 2002;87(7): 3433—
69.
70. Mitsutake N., Namba H., Takahara
71. K.,Ishigaki K., Ishigaki J., Ayabe H.,
72. Yamashita S.Tie-2 and angiopoietin-1
73. expression in human thyroid tumors. Thyroid
74. ; 12(2): 95—99.
75. Saenko V.A., Rogounovitch T.I,
76. Abrosi-movA.Y., Takamura N., Lushnikov E.F.,
77. Namba H.,Yamashita S. Problem of prevalence
78. of ret/PTC rearrangements in thyroid tumors.
79. Thyroid 2002;12(5): 435—434.
80. Rogounovitch T.I., Saenko V.A.,
81. S-YoshidaY., Abrosimov A.Y., Lushnikov
82. E.F.,RoumiantsevP.O., Ohtsuru A., Namba K,
83. Tsyb A.F.,Yamashita S. Large deletions in
84. mitochondrial DNA 1in radiation associated
85. human thyroid tumors. Can-cer Res 2002; 62:
86. —7041.
Рецензия
Для цитирования:
Yamashita Sh. MEDICAL AID AND RESEARCH PROJECTS FROM NAGASAKI ON RADIATION HEALTH EFFECTS AROUND CHERNOBYL. Проблемы здоровья и экологии. 2004;(1):7-10. https://doi.org/10.51523/2708-6011.2004-1-1-1
For citation:
Yamashita S. MEDICAL AID AND RESEARCH PROJECTS FROM NAGASAKI ON RADIATION HEALTH EFFECTS AROUND CHERNOBYL. Health and Ecology Issues. 2004;(1):7-10. (In Russ.) https://doi.org/10.51523/2708-6011.2004-1-1-1