Ischemic-Cervical Insufficiency as a Risk Factor for Intrauterine Infection
https://doi.org/10.51523/2708-6011.2019-16-4-5
Abstract
Objective: to study the clinical and morphological parallels in women with ischemic-cervical insufficiency (ICI) and to analyze the relationship between the development of intrauterine infection (IUI) of the fetus and the outcome of pregnancy.
Material and methods. Pregnant women (n = 88) with corrected pessaries of ICI (main group) were examined, in 32 of which pregnancy ended in premature birth and in term birth in 56 women. The control group consisted of 30 women with the physiological course of pregnancy. The course of pregnancy has been analyzed, the morphological features of the fetoplacental complex and the health status of the newborns have been studied.
Results. Regardless of the term of labor, the patients with ICI have an increased risk for IUI in the newborn by 36 times compared with the control group (p = 0.012), and inflammatory changes in the placenta are observed in 96.6 % of the cases (2р(F) < 0.0001). In spontaneous preterm birth associated with ICI, chorioamnionitis is observed 7.3 times more often (p = 0.0005) than in urgent birth and is related to premature rupture of the fetal membranes (r = 0.34; p = 0.023) and is 3 times more often accompanied by the development of IUI of the newborn (p = 0.017).
Conclusion: ICI is an important risk factor for intrauterine infection and the development of intrauterine infection of the newborn, which must be taken into account in the management of pregnancy in patients with ICI.
About the Authors
T. N. Zakharenkova
Gomel State Medical University
Belarus
Belarus
Zakharenkova T.N., PhD, Associate Professor, Head of the Department of Obstetrics and Gynecology with the course of the Faculty of Professional Development and Retraining of the educational institution «Gomel State Medical University».
Yu. D. Kaplan
Gomel State Medical University
Belarus
Belarus
Kaplan Yu.D., assistant of the Department of Obstetrics and Gynecology with the course of the Faculty of Professional Development and Retraining of the EI «Gomel State Medical University».
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Review
For citations:
Zakharenkova T.N., Kaplan Yu.D. Ischemic-Cervical Insufficiency as a Risk Factor for Intrauterine Infection. Health and Ecology Issues. 2019;(4):27-32. (In Russ.) https://doi.org/10.51523/2708-6011.2019-16-4-5
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