Preview

Health and Ecology Issues

Advanced search

PRACTICAL ASPECTS FOR DONOR SELECTION FOR UNRELATED TRANSPLANTATION OF HEMOPOIETIC STEM CELLS

https://doi.org/10.51523/2708-6011.2011-8-2s-29

Abstract

In cases when there is no HLA-compatible related donor, an unrelated donor is searched for in the data bases of international and national registers of donors for hemopoietic stem cells. The Minsk Municipal Registе of donors for marrow and hemopoietic stem cells was founded in 2009. At present it contains the data on more than 3,5 thousand donors described by HLA-phenotype. The HLA-typing Laboratory was organized in 2010 in Municipal Clinical Hospital № 9. Its main tasks are donor typing for Minsk Municipal register of donors for marrow and hemopoietic stem cells and to select pairs of donor-recipient for allogenic transplantation. Accreditation of HLA-typing Laboratory by European Federation of Immunogenetics and including of the national register into the IBMTR data base are a prospective goal.

About the Authors

A. Yu. Startseva
Municipal Clinical Hospital № 9
Belarus


E. A. Yanushevskaya
Municipal Clinical Hospital № 9
Belarus


A. L. Uss
Municipal Clinical Hospital № 9
Belarus


S. I. Krivenko
Municipal Clinical Hospital № 9
Belarus


References

1. Зарецкая, Ю. М. HLA. 50 лет: 1958-2008 / Ю. М. Зарецкая, Ю. А. Леднев. - Триада, 2008.

2. Donor selection process for allogeneic hematopoietic stem cell transplantation at the university hospital of Düsseldorf (1997-1998) / J. Enczmann [et al.] // Bone Marrow Donor Center with Eurocord Bank and Transplantation Immunology, Heinrich Heine University Medical Center, Düsseldorf, Germany.

3. Hematopoietic Stem Cell Transplantation / M. Hert [et al.] // Blood. - 2006. - Vol. 15. - P. 32-40.

4. Hematopoietic Stem Cell Transplantation // V. Samavedi [et al.] // Blood. - 2007. - Vol. 45. - P. 26-28.

5. High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation / S. J. Lee [et al.] // Blood. - 2007. - Vol. 110(13). - P. 4576-4583.

6. The detection of donor-directed, HLA-specific alloantibodies in recipients of unrelated hematopoietic cell transplantation is predictive of graft failure / S. Spellman [et al.] // Blood. - 2010. - Vol. 115, № 13. - Р. 132-140.


Review

For citations:


Startseva A.Yu., Yanushevskaya E.A., Uss A.L., Krivenko S.I. PRACTICAL ASPECTS FOR DONOR SELECTION FOR UNRELATED TRANSPLANTATION OF HEMOPOIETIC STEM CELLS. Health and Ecology Issues. 2011;(2S):83-85. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-2s-29

Views: 225


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)