EFFICACY OF THE COMBINED APPLICATION OF HEMOPOIETIC GROWTH FACTORS AFTER STEM HEMOPOIETIC CELL TRANSPLATATION
https://doi.org/10.51523/2708-6011.2011-8-2s-18
Abstract
The restoration of hemopeisis indices after high dose chemotherapy with autologic and allogenic transplantation of stem hemopoeitic cells with the combined use of hemopoietic growth factors - erythropoietin and granulocytic colony-stimulating factor at the early post-trasplantation period has been studied. 268 patients were included into the investigation. The shortening of restoration terms of hemoglobin, leucocytes and neutrophils in the group of patients, undergoing the combined therapy of hemopoietic growth factors after autologic transplantation of stem hemopoeitic cells. The shortening of restoration terms of hemoglobin, leucocytes and neutrophils in the group of patients, undergoing the combined therapy of hemopoietic growth factors after allogenic marrow transplantation. In whole, the application of erythropoietin in the combination of with granulocyte colony-stimulating factor led to the decreased hematologic toxicity.
About the Authors
E. A. Kuzmich
Republican Research Center for Hematology and Transfusiology
Belarus
Belarus
V. A. Zmachinsky
Belarussian Medical Academy for Postgraduate Education
Belarus
Belarus
N. F. Milanovich
Minsk Municipal Clinical Hospital № 9
Belarus
Belarus
N. A. Novosiolova
United Institute for Information Science Problems NAS of Belarus
Belarus
Belarus
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Review
For citations:
Kuzmich E.A., Zmachinsky V.A., Milanovich N.F., Novosiolova N.A. EFFICACY OF THE COMBINED APPLICATION OF HEMOPOIETIC GROWTH FACTORS AFTER STEM HEMOPOIETIC CELL TRANSPLATATION. Health and Ecology Issues. 2011;(2S):57-59. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-2s-18
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