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DIAGNOSTIC SIGNIFICANCE OF LABORATORY MARKERS FOR ANTIPHOSPHOLIPID SYNDROME IN SYSTEMIC LUPUS ERYTHEMATOSUS

https://doi.org/10.51523/2708-6011.2011-8-2s-2

Abstract

The levels of the laboratory markers for antiphospholipid syndrome, i.e. cardiolipin autoantibodies and antibodies to β2-glycoprotein 1 IgG and IgM in systemic lupus erythematosus have been studied. It has been established that the increase of the marker level of antiphospholipid syndrome is observed in 67 % systemic lupus erythematosus cases. The IgG autoantibodies are mоre often detected in the development of secondary antiphospholipid syndrome.

About the Authors

N. A. Bashlakova
Belarusian Medical Academy of Postgraduate Education
Belarus


D. V. Shubenok
Republican Research Center for Pediatric Oncology and Hematology
Belarus


Z. I. Kravchuk
Belarusian Medical Academy of Postgraduate Education
Belarus


S. P. Martsev
Republican Research Center for Pediatric Oncology and Hematology
Belarus


T. D. Tyabut
Belarusian Medical Academy of Postgraduate Education
Belarus


References

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3. Pathogenetic anti-β2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a comformational change / B. de Laat [et al.] // Blood. - 2006. - Vol. 107, № 5. - P. 1916-1924.

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For citations:


Bashlakova N.A., Shubenok D.V., Kravchuk Z.I., Martsev S.P., Tyabut T.D. DIAGNOSTIC SIGNIFICANCE OF LABORATORY MARKERS FOR ANTIPHOSPHOLIPID SYNDROME IN SYSTEMIC LUPUS ERYTHEMATOSUS. Health and Ecology Issues. 2011;(2S):18-20. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-2s-2

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ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)