ПРЕПАРАТЫ РАСТОРОПШИ: МЕХАНИЗМЫ ДЕЙСТВИЯ И ПРИМЕНЕНИЕ ПРИ ЗАБОЛЕВАНИЯХ ПЕЧЕНИ
https://doi.org/10.51523/2708-6011.2009-6-4-6
Аннотация
Об авторах
Ю. И. БрельБеларусь
А. Н. Лызиков
Беларусь
Э. С. Питкевич
Беларусь
Список литературы
1. Pharmacology of Silymarin / F. Fraschini [et al.] // Clin. Drug Invest. - 2002. - Vol. 22, № 1. - P. 51-65.
2. Silymarin treatment of viral hepatitis: a systematic review / K. E. Mayer [et al.] // Journal of Viral Hepatitis. - 2005. - Vol. 12. - P. 559-567.
3. Kren, V. Silybin And Silymarin - new effects and applications / V. Kren, D. Walterova // Biomed. Papers. - 2005. - Vol. 149, № 1. - P. 29-41.
4. Pharmacokinetic studies with silymarin in human serum and bile / D. Lorenz [et al.] // Methods Find. Exp. Clin. Pharmacol. - 1984. - Vol. 6, № 10. - P. 655-661.
5. Pradhan, S. C. Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine / S. C. Pradhan, C. Girish // Indian J. Med. Res. - 2006. - Vol. 124, № 5. - P. 491-504.
6. Effect of free radical scavengers on superoxide dismutase (SOD) enzyme in patients with alcoholic cirrhosis / J. Feher [et al.] // Acta Medica Hungarica. - 1988. - Vol. 45, № 3/4. - P. 265-276.
7. Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver / R. Campos [et al.] // Planta Med. - 1989. - Vol. 55, № 5. - P. 417-419.
8. Sonnenbichler, J. Mechanism of action of silibinin. V. Effect of silibinin on the synthesis of ribosomal RNA, mRNA and tRNA in rat liver in vivo / J. Sonnenbichler, I. Zetl // Hoppe Seylers Z Physiol. Chem. - 1984. - Vol. 365, № 5. - P. 555-566.
9. Inhibition of Kupffer cells as an explanation for the hepatoprotective properties of silibinin / C. Dehmlow [et al.] // Hepatology. - 1996. - Vol. 24, № 4. - P. 749-754.
10. Selective inhibition of NF-kB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways / C. Saliou [et al.] // FEBS Lett. - 1998. - Vol. 440. - P. 8-12.
11. Effects of silibinin and of a synthetic analogue on isolated rat hepatic stellate cells and myofibroblasts / E. C. Fuchs [et al.] // Arzneimittelforschung. - 1997. - Vol. 47, № 12. - P. 1383-1387.
12. Characterization of a transporting system in rat hepatocytes: studies with competitive and noncompetitive inhibitors of phalloidin transport / K. Munter [et al.] // Biochem. Biophys. Acta. - 1986. - Vol. 860, № 1. - P. 91-98.
13. Silymarin: potent inhibitor of cyclic AMP phosphodiesterase / H. P. Koch [et al.] // Methods Find. Exp. Clin. Pharmacol. - 1985. - Vol. 7, № 8. - P. 409-413.
14. Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells / A. Tyagi [et al.] // Prostate. - 2002. - Vol. 153, № 3. - P. 211-217.
15. Antitumour activity of the silybin-phosphatidylcholine complex IdB 1016, against human ovarian cancer / D. Gallo [et al.] // Eur. J. Cancer. - 2003. - Vol. 39. - P. 2403-2410.
16. Anticancer potential of silymarin: from bench to bed side / R. Agarwal [et al.] // Anticancer Res. - 2006. - Vol. 26, № 6B. - P. 4457-4498.
17. The flavonoid silibinin decreases glucose-6-phosphate hydrolysis in perfused rat hepatocytes by an inhibitory effect on glucose-6-phosphatase / B. Guigas [et al.] // Cell Physio. Biochem. - 2007. - Vol. 20, № 6. - P. 925-934.
18. Skottova, N. Silymarin as a potential hypocholesterolaemic drug / N. Skottova, V. Kreeman // Physiol Res. - 1998. - Vol. 47. - P. 1-7.
19. Silymarin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity by inhibiting microglia activation / M. J Wang [et al.] // Eur. J. Neurosci. - 2002. - Vol. 16. - P. 2103-2112.
20. Jung, H. J. Synergistic antibacterial effect between silybin and N,N'-dicyclohexylcarbodiimide in clinical Pseudomonas aeruginosa isolates / H. J. Jung, D. G. Lee // J. Microbiol. - 2008. - Vol. 46, № 4. - P. 462-467.
21. In vitro antimalarial activity of flavonoid derivatives dehydrosilybin and 8-(1;1)-DMA-kaempferide / De F. Monbrison [et al.] // Acta Trop. - 2006. - Vol. 97, № 1. - P. 102-107.
22. Ethanol elimination in man under influence of hepatoprotective silibinin / M. Varga [et al.] // Blutalkohol. - 1991. - Vol. 28, № 6. - P. 405-408.
23. Liver protective action of silymarin therapy in chronic alcoholic liver diseases / I. Feher [et al.] // Orv. Hetil. - 1989. - Vol. 130. - P. 2723-2727.
24. Salmi, H. A. Effects of silymarin on chemical, functional and morphological alterations of the liver. A double-blind controlled study / H. A. Salmi, S. Sarna // Scand. J. Gastroenterol. - 1982. - Vol. 17. - P. 517-521.
25. Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis Results of a randomized, double-blind, placebo-controlled clinical study / M. I. Lucena [et al.] // Int. J. Clin. Pharmacol. Therapeut. - 2002. - Vol. 40, № 1. - P. 2-8.
26. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver / P. Ferenci [et al.] // J. Hepatol. - 1989. - Vol. 9, № 1. - P. 105-113.
27. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial / A. Pares [et al.] // J. Hepatol. - 1998. - Vol. 28, № 4. - P. 615-621.
28. Protection by silibinin against Amanita phalloides intoxication in beagles / G. Vogel [et al.] // Toxicol. Appl. Pharmacol. - 1984. - Vol. 73. - P. 355-362.
29. Treatment of amatoxin poisoning: 20-year retrospective analysis / F. Enjalbert [et al.] // J. Toxicol. Clin. Toxicol. - 2002. - Vol. 40, № 6. - P. 715-757.
30. Chemotherapy of Amanita phalloides poisoning with intravenous silibinin / K. Hruby [et al.] // Hum. Toxicol. - 1983. - Vol. 2, № 2. - P. 183-195.
31. Results of a double blind study on the effect of silymarin in the treatment of acute viral hepatitis, carried out at two medical centres / E. Magliulo [et al.] // Med. Klin. - 1978. - Vol. 73, № 28/29. - P. 1060-1065.
32. Therapeutic effect of silipide in patients with chronic hepatitis C non-responders (NTs) to interferon (IFN) treatment / G. Buzzelli [et al.] // J. Hepatol. - 1994. - Vol.21, № 1. - P. 100.
33. A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB1016) in chronicactive hepatitis / G. Buzzelli [et al.] // Int. J. Clin. Pharmacol. Ther Toxicol. - 1993. - Vol. 31, № 9. - P. 456-460.
34. Randomized open study of the dose-effect relationship of a short course of IdB 1016 in patients with viral or alcoholic hepatitis / A. Vailati [et al.] // Fitoterapia. - 1993. - Vol. 64, № 3. - P. 219-228.
35. Treatment with silybin-vitamin E-phospholipid complex in patients with hepatitis C infection / K. Falasca [et al.] // J. Med. Virol. - 2008. - Vol. 80, № 11. - P. 1900-1906.
Рецензия
Для цитирования:
Брель Ю.И., Лызиков А.Н., Питкевич Э.С. ПРЕПАРАТЫ РАСТОРОПШИ: МЕХАНИЗМЫ ДЕЙСТВИЯ И ПРИМЕНЕНИЕ ПРИ ЗАБОЛЕВАНИЯХ ПЕЧЕНИ. Проблемы здоровья и экологии. 2009;(4):36-42. https://doi.org/10.51523/2708-6011.2009-6-4-6
For citation:
Brel Y.I., Lyzikov A.A., Pitkevich E.S. HETRBAL PREPARATIONS FROM MILK THISTLE: MECHANISMS OF ACTION AND APPLICATION IN LIVER DISEASES. Health and Ecology Issues. 2009;(4):36-42. (In Russ.) https://doi.org/10.51523/2708-6011.2009-6-4-6