PEROXYNITRITE-INDUCED RED BLOOD CELL APOPTOSIS
https://doi.org/10.51523/2708-6011.2009-6-1-25
Abstract
Though red blood cells contain no apoptotic organelles like nuclei and mitochondria, under the action of various factors these cells are characterized by many features peculiar to apoptotic cells. In the paper we show that «apoptosis-like» cell death program is triggered by peroxynitrite and is accompanied by the increase in passive ionic flux through red blood cell membrane mainly due to opening the cationic channels including ATP-sensitive K+ channels and membrane defect formation, as well as by the changes in membrane skeleton structure.
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Review
For citations:
Starodubtseva M.N. PEROXYNITRITE-INDUCED RED BLOOD CELL APOPTOSIS. Health and Ecology Issues. 2009;(1):117-122. (In Russ.) https://doi.org/10.51523/2708-6011.2009-6-1-25
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