TRAUMATIC MODEL OF ACUTE AND CHRONIC PANCREATITIS

Abstract

Surgical methods of modeling of cysts of the acute and chronic pancreases are generalized, the critical estimation is given. The original traumatic way of reproduction of the experimental pancreas, where the basis is the local cold influence on the pancreas of white rat with the help of cryosurgical complex KCH 3A/B is offered. The work was done with the observance of the rules stipulated by the European Commission on supervision of carrying out laboratory and other experiments with participation of experimental animals of different kinds. Cooling was carried out intraoperatively, by the direct contact of the cryosurgical tip with the tissue of the pancreas. The features of morphological changes, depending on the cooling temperature are established. The offered traumatic model of acute and chronic pancreas gives an opportunity to study mechanisms of the origin of the pathology and to approve the ways of the treatment.