CIRCULATION DINAMYCS OF SPECIFIC SERUM MARKERS OF HERPETIC (HSV, CMV) INFECTION ACTIVE REPLICATION IN POPULATION OF GOMEL REGION

Abstract

There was estimated infecting of Gomel Region population with Herpes Simplex Virus (HSV) and Cytomegalovirus (CMV). There was determined frequency of reactivation of above-mentioned infections during the calendar year. Determination of serum markers to HSV and CMV was carried out by means of quantitative method of hard-phase Immuno-Enzyme-Analysis (IEA) on test-systems of «Equipar-SRL-Diagnostici» firm. Blood serums of 551 people were subjected to one-moment analysis. 106 donors of blood plasma at the age of 20-49 years old were taken for the observation to determine HSV and CMV infection. In the process of the investigation there was determined that the level of HSV and CMV infecting appeared to be 96,4 and 92,4 % relatively. 30,2 % of the examined people were in the state of active HSV infection, 16,5 % - in the state of active CMV infection. Frequent HSV infection reactivation during the year was revealed in 73,6 ± 4,3 % people; CMV infection - in 32,1 ± 4,5 %. There was determined the seasonal relapse of herpetic infection with prevalence of infectious process activation during winter-spring time.