INFLAMMATION MARKERS AT PREMATURE RUPTURE OF AMNIOTIC MEMBRANES
https://doi.org/10.51523/2708-6011.2009-6-1-16
Abstract
Purpose: reveale role: lactoferrin, interferon-ά, interferon-γ, interleukin-1β, receptor antagonist interleukin-1β at premature rupture amniotic membranes. Material and method: ELISA detected concentration of lactoferrin, interferon-ά, interferon-γ, interleukin-1β, receptor antagonist interleukin-1β in peripheral blood, umbilical blood, amniotic fluid. Statistica: Mann-Whitney Т & U-test, Spearman rank, calculation median, odds ratio and confidence interval. Results: аt premature rupture amniotic membranes lactoferrin in peripheral blood is lower (р < 0,005), and IL-1β - is higher (р < 0,02), than at duly. At duly rupture RA-IL-1β concentration in amniotic fluid is increased in comparison with umbilical (р < 0,001) and mather’s blood (р < 0,001). The increase in duration waterless interval raises ά-IF (р = 0,05) level and is reduced lactoferrin (р = 0,02) in umbilical blood.
About the Authors
I. A. Korbut
Gomel State Medical University
Belarus
Belarus
E. I. Baranovskaja
Gomel State Medical University
Belarus
Belarus
E. V. Voropayev
Gomel State Medical University
Belarus
Belarus
L. G. Barry
Gomel State Medical University
Belarus
Belarus
N. M. Golubyh
Gomel State Medical University
Belarus
Belarus
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Review
For citations:
Korbut I.A., Baranovskaja E.I., Voropayev E.V., Barry L.G., Golubyh N.M. INFLAMMATION MARKERS AT PREMATURE RUPTURE OF AMNIOTIC MEMBRANES. Health and Ecology Issues. 2009;(1):78-83. (In Russ.) https://doi.org/10.51523/2708-6011.2009-6-1-16
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