A TYPE IS SPECIFICITY THE FEATURE OF PAPILLOMAVIRUS INFECTION FOR HEALTHY WOMEN AND PATIENTS WITH PATHOLOGY OF CERVICAL UTERUS

Abstract

The type is specifity features of papillomavirus infection are studied in 311 women. All inspected women were parted on two basic groups, I group - healthy virus-transmitter is a 101 woman, the II group is patients with different pathology the cervical of uterus (koylocytis of multi-layered flat epithelium, koylocyte CIN I-III, intraepitilial and invasion cancer the cervical of uterus) are 210 patients. At the study of frequency and features of virus-transmitter for healthy patients, it is exposed, that the infected in this group - 36,6 ± 5,0% (37 women). The most frequent type in the group of healthy women was HPV HCR (high cancerogen risk) 16 (59,4 ± 8,1%); practically HPV HCR 56 (16,22 ± 6,1%) and HPV MCR (middle cancerogen risk) 31 and 58 types (18,92 ± 6,4% and 16,22 ± 6,1% accordingly) met with identical frequency, while 18 a type is exposed only for 4th women (10,8 ± 5,1%). For women with HPV diagnosed the associated pathology of cervical uterus of HPV HCR at 75,68 ± 7,0%, thus most often at patients withcervical cancer - 95,4 ± 2,6%. Among HPV HCR most often there is HPV 16 type - 64,7 ± 3,3% (p < 0,05); among HPV MCR exuded HPV 58 type, meeting more frequent both in a general group (18,1 ± 2,6%) and at patients with advanced cervical cancer (31,8 ± 5,7%), thus distinctions of frequency of virus- transmitter HPV 58 type at patients with advanced cervical cancer, HSIL and LSIL statistically meaningful (p = 0,005 and 0,02 accordingly). This fact also can be delivered to the epidemiology feature of our region.