LABORATORY AND CLINICAL CHANGES OF ANTIRETROVIRAL THERAPY

Abstract

In the article we can determine changes of parameters of the general and biochemical analyses of blood, also me can find clinical displays at patients on the various schemes of antiretroviral therapy applied to treatment of a HIV-infected in the Gomel regional infectious hospital are presented. It is revealed, that at the HIV-infected receiving various schemes of antiretroviral therapy, in 1-6 months of treatment the individual clinically expressed by-effects leading a cancelling or change of the scheme of antiretroviral therapy were observed. On the scheme: combivir + stocrin leading change were registered hematologic changes (heavy anemia) in 11, 8% of cases therefore scheme of therapy was changed. At the patients was on the scheme combivir +virasept, in 1 month from the beginning of treatment the maintenance of the general bilirubin in whey of blood authentically increased. Among the patients received stocrin + epivir + zerit, in 1 month from the beginning of treatment activity α- -amylase authentically increased. At the majority of patients with revealed аnti-HCVtot with presence of biochemical activity on a background of treatment parameters ALT were normalized.