Preview

Health and Ecology Issues

Advanced search

THE RESULTS OF RADIOIODINE TREATMENT IN PATIENTS WITH THYROTOXICOSIS IN THE REPUBLIC OF BELARUS

https://doi.org/10.51523/2708-6011.2008-5-3-3

Abstract

The study was undertaken to evaluate the efficacy of radioiodine therapy in 46 patients with thyrotoxicosis who received treatment in the Republic of Belarus. Results: a statistically significant decrease in the size of the thyroid gland by 71,9% was noted during 12 months after the therapy; radioiodine treatment causes a decrease in thyroid nodule volume. Within 1 year of treatment the desired therapeutic effect (hypothyroidism) was noted in 76,9% of the patients; hypothyroidism, requiring replacement therapy, is most actively noticeable after the first 3 months following the therapy.

About the Authors

S. S. Galitskaya
Belarussian State Medical University
Belarus


T. V. Mokhort
Belarussian State Medical University
Belarus


I. V. Krutko
Gomel Regional Endocrinological Dispensary
Belarus


References

1. Валуевич, В. В. Радиойодтерапия функциональной автономии щитовидной железы / В. В. Валуевич // Здравоохранение. - 2005. - № 10. - С. 33-38.

2. Данилова, Л. И. Радиойодтерапия доброкачественных заболеваний щитовидной железы / Л. И. Данилова, В. В. Валуевич // Проблемы эндокринологии. - 2006. - № 2. - С. 43-47.

3. Мохорт, Т. В. Эффективность лечения пациентов с диффузным токсическим зобом радиоактивным йодом: данные 12-месячного наблюдения / Т. В. Мохорт, Н. В. Карлович, Е. И. Кузьменкова // Актуальные проблемы патологии щитовидной железы. Матер. научно-практ. конф. «Международное сотрудничество в области изучения патологии щитовидной железы». - Гомель, 2005. - С.60-64.

4. Отдаленные результаты лечения токсического зоба радиоактивным I-131 / В. В. Фадеев [и др.] // Проблемы эндокринологии. - 2005. - № 1. - С. 3-10.

5. Эффективность и безопасность радиойодтерапии болезни Грейвса / Г. В. Шестакова [и др.] // Проблемы эндокринологии. - 2007. - № 5. - С. 24-27.

6. American association of clinical endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism // Endocrine practice. - 2002. - Vol. 8, № 6. - P. 457-467.

7. Franklyn, J. A. Thyroid Function and Mortality in Patients Treated for Hyperthyroidism / J. A. Franklyn, M. C. Sheppard, P. Maisonneuve // JAMA. - 2005. - Vol. 294. - Р. 71-80.

8. Iodine-131:Optimal therapy for hyperthyroidism in children and adolescents? / J. E. Freitas [et al.] // J Nucl Med. - 1979. - Vol. 20. - P. 847-848.

9. Hertz, S. A. Application of radioactive iodine in therapy of Graves’ disease / S. Hertz, A. Roberts // J Clin Invest. - 1942. - Vol. 21. - P. 624.

10. Reduction in thyroid volume after radioiodine therapy of Grave’s hyperthyroidism: results of a prospective, randomized, multicentre study / H. Peters [et al.] // European Journal of Clinical Investigation. - 1996. - Vol. 26, № 1. - Р. 59-63.

11. -year retrospective analysis of the efficacy and safety of radioactive iodine in treating young Graves’ patients / C. H Read, M. J. Tansey, А. Menda // J Clin Endocrinol Metab. - 2004. - Vol. 89. - P. 4229-4233.

12. Rivkees, S. A. Influence of iodine-131 dose on the outcome of hyperthyroidism in children / S. A. Rivkees, E. A. Cornelius // Pediatrics. - 2003. - Vol. 111. - P. 745-749.

13. Cancer mortality following treatment for adult hyperthyroidism: Cooperative Thyrotoxicosis Follow-up study Group / E. Ron [et al.] // JAMA. - 1998. - Vol. 280. - P. 347-355.


Review

For citations:


Galitskaya S.S., Mokhort T.V., Krutko I.V. THE RESULTS OF RADIOIODINE TREATMENT IN PATIENTS WITH THYROTOXICOSIS IN THE REPUBLIC OF BELARUS. Health and Ecology Issues. 2008;(3):15-19. (In Russ.) https://doi.org/10.51523/2708-6011.2008-5-3-3

Views: 263


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)