REPRODUCTION CYSTS OF THE PANCREAS IN THE EXPERIMENT

Abstract

Surgical methods of modelling of cysts of the pancreas are generalized, the critical estimation is given. The original way of reproduction of pseudocysts of pancreas of a white rat, where the basis is the local cold influence on the pancreas with cryosurgical complex KCH 3A/B is offered. The work was done with the observance of the rules stipulated by the European Commission on supervision of carrying out laboratory and other experiments with participation of experimental animals of different kinds. Cooling was carried out intraoperatively, by the direct contact of the cryosurgical tip with the tissue of the pancreas. It is established that after the cryoinfluence from -60 C to -180 C for 40 and more seconds, pseudocyst of the pancreas, containing necrosative tissue, inflammatory эксудат and pancreatic juice is formed. The presented way is simple in its execution and allows to get the necessary result in 100% cases. The offered model of the pseudocyst of the pancreas gives an opportunity to study mechanisms of the origin of the pathology and to approve the ways of the treatment.