HERPETIC (HSV, CMV), CHLAMYDIAL (СHLAMYDOPHILIA PNEUMONIAE), MYCOPLASMYC (MYCOPLASMA PNEUMONIAE) INFECTIONS AND ABDOMINAL ATHEROSCLEROSIS

Abstract

There was performed the analysis of local markers distribution (genomic DNA and antigen material) HSV, CMV, С.pneumoniae (СР) и M.pneumoniae (МР) in the endothelium of the abdominal aorta taking into account morphologic characteristics of the vascular wall. Vessels samples of 89 corpses (35,2 ± 9,8 years old) were included into the investigation. There was revealed a high index of atherosclerotic samples lesions of abdominal aorta for the studied Gomel region population at the age of 20-49 years old (94,4%). As the result of polymerase chain reaction (PCR) analysis of atherosclerotically changed vessels samples HSV genome was revealed in 59,5% of cases, CMV - 52,4%, CР - 45,2%, MР - 67,9%. Revelation indices of genomic DNA HSV, CMV, СР, МР for died of atherosclerosis manifestations (n = 25) and from accidental causes (n = 64) were approximately at the same level (P > 0,05). Antigen material of the studied pathogens was reliably more often revealed in the group of people died of atherosclerosis (P < 0,05). The received results correspond with infectious inflammatory conception of atherosclerosis.