Preview

Health and Ecology Issues

Advanced search

DYNAMICS OF BLOOD CORTISOL LEVELS IN ABDOMINAL AORTIC SURGERY IN CONDITIONS OF MULTICOMPONENT WELL-BALANCED ANESTHESIA

https://doi.org/10.51523/2708-6011.2018-15-2-6

Abstract

Objective: to evaluate expression of stress hormonal response in reconstructive abdominal aortic surgery. Material and methods. The level of blood cortisol in patients operated for stenosing disorders and atherosclerotic aneurisms of the infrarenal aorta has been studied. Results. The patients recorded a statistically significant increase of the cortisol level during the stage of the clamping of the aorta - by 1.98 times in comparison with the preoperative one; during the stage of termination of the operation the level of blood serum cortisol did not show a statistically significant change and stayed to be increased by 1.79 times. Conclusion . The increase of the blood serum cortisol from 340.84 nmol/l at the admission of a patient into an operating theatre up to 676.19 nmol/l 3-5 minutes later after the clamping of the aorta and up to 613.51 nmol/l at the end of the operational intervention is a stress-norm in abdominal aortic surgery in conditions of multicomponent well-balanced anesthesia with application of propofol and fentanyl.

About the Authors

D. V. Osipenko
Gomel Regional Cardiologic Center
Belarus


A. A. Skorohodova
Gomel Regional Cardiologic Center
Belarus


References

1. ЛИТЕРАТУРА

2. Miller RD, Eriksson LI, Fleisher LA, Wiener-Kronish JP, Young WL. Miller's anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2009.

3. Иоскевич НН. Болезни органов грудной клетки, сосудов, селезенки и эндокринных желёз: практ. руководство по клин. хирургии. Минск, РБ: Вышэйшая школа; 2002.

4. Hertzer NR. Current status of endovascular repair of infrarenal abdominal aortic aneurysms in the context of 50 years of conventional repair. Ann N Y Acad Sci. 2006;1085:175-86.

5. Зильбер АП. Клиническая физиология в анестезиологии и реаниматологии. Москва, РФ: Медицина; 1984. 480с.

6. Овечкин АМ. Хирургический стресс-ответ, его патофизиологическая значимость и способы модуляции. Регионарная Анестезия и Лечение Острой Боли. 2008;2(2):49-62.

7. Morgan GE, Mikhail MS. Clinical anesthesiology. 2nd ed. Stamford, Connecticut; London: Prentice-Hall International; 1996.

8. Марочков АВ, Осипенко ДВ, Дорогокупец ВМ, Шматько ДП. Опыт анестезиологического обеспечения и особенности течения раннего послеоперационного периода при реконструктивных операциях на брюшном отделе аорты. Новости Хирургии. 2010;18(1):90-100.

9. Jaffe RA, Samuels SI. Anesthesiologist's manual of surgical procedures. New York: Raven Press; 1994.

10. Kataja J, Chrapek W, Kaukinen S, Pimenoff G, Salenius JP. Hormonal stress response and hemodynamic stability in patients undergoing endovascular vs. conventional abdominal aortic aneurysm repair. Scand J Surg. 2007;96(3):236-42.

11. Максимов АВ, Фейсханов АК, Плотников МВ, Бегичева ЕВ, Туишева ЕВ. Динамика содержания кортизола плазмы крови в периоперационном периоде при различных доступах к артериям аортобедренного сегмента. Казанский Медицинский Журн. 2012;93(5):717-20.

12. Calogero AE, Norton JA, Sheppard BC, Listwak SJ, Cromack DT, Wall R, et al. Pulsatile activation of the hypothalamic-pituitary-adrenal axis during major surgery. Metabolism. 1992; 41(8):839-45.


Review

For citations:


Osipenko D.V., Skorohodova A.A. DYNAMICS OF BLOOD CORTISOL LEVELS IN ABDOMINAL AORTIC SURGERY IN CONDITIONS OF MULTICOMPONENT WELL-BALANCED ANESTHESIA. Health and Ecology Issues. 2018;(2):28-33. (In Russ.) https://doi.org/10.51523/2708-6011.2018-15-2-6

Views: 343


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)