Overlap syndrome in hepatology
O. A. Yarmolenko,
E. G. Malaeva,
I. L. Mamchenko,
T. V. Aleynykova,
L. A. Kobruseva,
I. A. Khudyakov,
M. N. Menshakova,
E. I. Malasсhenko https://doi.org/10.51523/2708-6011.2023-20-2-17
Abstract
Autoimmune liver disease is a heterogeneous group of diseases in which the body’s immune cells and antibodies are directed against its own components of the liver tissue. The main diseases from this group are: autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis. Most often there are classical monovariants of the disease, but in some cases, manifestations of two forms from the autoimmune liver disease are observed at once. The term “overlap syndrome” is used to describe such conditions. The article presents a clinical case of a combination of PBC and AIH, one of the most common overlapping syndromes in practice. Most often there are classical monovariants of the disease, but in some cases there are manifestations of two forms of autoimmune liver diseases. Overlap syndrome is a term used to describe these conditions. This article presents a clinical case of a combination of PBC and AIH, one of the most common cross-linked syndromes in practice.
About the Authors
O. A. Yarmolenko
Gomel State Medical University
Belarus
Belarus
Olga A. Yarmolenko, Senior Lecturer at the Department of Internal Medicine No. 1 with the courses of Endocrinology and Hematology
Gomel
E. G. Malaeva
Gomel State Medical University
Belarus
Belarus
Ekaterina G. Malaeva, Candidate of Medical Sciences, Associate Professor, Head of the Department of Internal Medicine No 1 with the courses of Endocrinology and Hematology
Gomel
I. L. Mamchenko
Gomel State Medical University
Belarus
Belarus
Inna L. Mamchenko, Assistant Lecturer of the Department of Internal Medicine No 1 with the courses of Endocrinology and Hematology
Gomel
T. V. Aleynykova
Gomel State Medical University
Belarus
Belarus
Tetyana V. Aleynykova, Senior Lecturer at the Department of Internal Medicine No. 1 with the courses of Endocrinology and Hematology
Gomel
L. A. Kobruseva
Gomel City Clinical Hospital No. 3
Belarus
Belarus
Larisa А. Kobruseva, Head of the Gastroenterology Department
Gomel
I. A. Khudyakov
Gomel City Clinical Hospital No. 3
Belarus
Belarus
Ivan А. Khudyakov, Head Doctor
Gomel
M. N. Menshakova
Gomel City Clinical Hospital No. 3
Belarus
Belarus
Marina N. Menshakova, Deputy Head Doctor for Medicine
Gomel
E. I. Malasсhenko
Gomel City Clinical Hospital No. 3
Belarus
Belarus
Elena I. Malasсhenko, Deputy Head Doctor for Organization and Methodology
Gomel
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Review
For citations:
Yarmolenko O.A., Malaeva E.G., Mamchenko I.L., Aleynykova T.V., Kobruseva L.A., Khudyakov I.A., Menshakova M.N., Malasсhenko E.I. Overlap syndrome in hepatology. Health and Ecology Issues. 2023;20(2):135-140. (In Russ.) https://doi.org/10.51523/2708-6011.2023-20-2-17
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