Laboratory criteria for early threatened miscarriage
https://doi.org/10.51523/2708-6011.2022-19-2-09
Abstract
Objective. To determine the role of placental growth factor, fibronectin, certain hemostatic parameters and glycodelin in the genesis of early miscarriage.
Materials and methods. Venous blood, inpatient medical records (form No.003/u-07), prenatal records (form No.113/u-07) of 94 pregnant women. The software package "Statistica" 10.0 and the programming language "R" version 4.1 were used for statistical analysis.
Results. Placental growth factor, fibronectin and glycodelin can be considered as laboratory markers of miscarriage during the first trimester of gestation.
Conclusion. The markers of early reproductive losses we have identified underlie the development of endothelial and hemostasiological disorders and morphofunctional inferiority of the endometrium.
About the Authors
L. V. Kastsova
Grodno State Medical University
Belarus
Belarus
Liubou V. Kastsova, postgraduate student at the Department of Obstetrics and Gynecology
Grodno
L. V. Gutikova
Grodno State Medical University
Belarus
Belarus
Ludmila V. Gutikova, DMedSc, Professor, Head of the Department of Obstetrics and Gynecology
Grodno
M. N. Kurbat
Grodno State Medical University
Belarus
Belarus
Mikhail N. Kurbat, PhD (Med), Associate Professor, Head of the Research Laboratory
Grodno
V. R. Shulika
Grodno State Medical University
Belarus
Belarus
Valentina R. Shulika, researcher at the Research Laboratoty
Grodno
A. Z. Kastsova
Grodno University Clinic
Belarus
Belarus
Ala Z. Kastsova, physician
Grodno
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Review
For citations:
Kastsova L.V., Gutikova L.V., Kurbat M.N., Shulika V.R., Kastsova A.Z. Laboratory criteria for early threatened miscarriage. Health and Ecology Issues. 2022;19(2):76-81. (In Russ.) https://doi.org/10.51523/2708-6011.2022-19-2-09
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