Comparative analysis of the course of COVID-19 in May 2020 and May 2021 in a hospital healthcare organization
https://doi.org/10.51523/2708-6011.2022-19-2-04
Abstract
Objective. To perform an analytical assessment of the dynamics of COVID-19 patients` state in the conditions of a hospital healthcare organization taking into account their comorbid diseases in May 2020 and May 2021, and to determine the prognostic indicators for a severe course of COVID-19.
Materials and methods. 96 medical records of COVID-19 patients who had undergone treatment at Gomel City Clinical Hospital No. 3 in May 2020 and 130 medical records of COVID-19 patients who had undergone treatment in May 2021 were retrospectively analyzed.
Results. The average age of women treated for pneumonia associated with COVID-19 at the hospital healthcare organization in 2020 was 58 years, in 2021 – 64.5 years, of men in 2020 – 58 years, in 2021 – 60.5 years. All patients underwent clinical examination according to temporary protocols. The most common COVID-19 comorbid background diseases in both 2020 and 2021 were coronary artery disease (CAD), arterial hypertension (AH), non-alcoholic fatty liver disease, diabetes mellitus (DM), kidney disease, and obesity. Polymorbidity in 2021 was observed 1.5 times more often than in 2020 (pFisher<0.001). C-reactive protein (CRP) and lactate dehydrogenase (LDH) levels are statistically associated with the severity of pneumonia (rS=0.33; p<0.001 and rS=0.2; p=0.03, respectively). The neutrophillymphocyte ratio (NLR) level in patients with a mild course of pneumonia associated with COVID-19 in 2020 was 1.58, in 2021 – 1.05, while in patients with a severe course in 2020 – 7.7, in 2021 – 10.63.
Conclusion. CRP, LDH and NLR serve as available methods for predicting the course of COVID-19 in comorbid patients in clinical practice.
About the Author
O. L. Nikiforova
Gomel State Medical University
Belarus
Belarus
Olga L. Nikiforova, Assistant Lecturer at the Department of Polyclinic Therapy and General Practice
Gomel
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For citations:
Nikiforova O.L. Comparative analysis of the course of COVID-19 in May 2020 and May 2021 in a hospital healthcare organization. Health and Ecology Issues. 2022;19(2):32–40. (In Russ.) https://doi.org/10.51523/2708-6011.2022-19-2-04
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