Correlation between the level of bacterial load and clinical characteristics of the course of the disease in patients with neuroischaemic diabetic foot
https://doi.org/10.51523/2708-6011.2021-18-1-6
Abstract
Objective: to analyze the clinical characteristics of the course of the disease in patients with neuroischaemic diabetic foot depending on the presence of bacterial monocultures and associations in wounds.
Material and methods. We have performed a comparative analysis of the parameters of the clinical course of the disease and the condition of patients’ wounds (n = 76) depending on the presence of monocultures (group 1, n = 32) and microbial associations (n = 42). The list of the compared parameters in the groups included the duration of diabetes, number of hospitalizations per year, achievement of target HbA1c levels (<7.5 %), condition of granulation tissue of wounds.
Results. With increased duration of the course of diabetes (from 5 to 15 years), higher number of hospitalizations per year, deteriorated carbohydrate metabolism (HbA1c> 7.5%) in combination with clinical signs of the initial stages of wound infection, the frequency rate of the detection of mixed bacterial cultures increased.
Conclusion. The work has found differences in the duration of the course of diabetes, the number of hospitalizations per year, local status of wounds in the patients, as well as the frequency of achieving the target levels of HbA1с <7.5 %, depending on the severity of microbial load.
About the Authors
V. I. Silvistrovich
Gomel State Medical University
Belarus
Belarus
Viktoriya I. Silvistrovich, Assistant Lecturer at the Department of Surgical Diseases No.1 with the course of Cardiovascular Surgery, Gomel
A. A. Lyzikov
Gomel State Medical University
Belarus
Belarus
Alexei A. Lyzikov, D.Sc. (Medicine), Professor, Head of the Department of Surgical Diseases No.1 with the course of Cardiovascular Surgery, Gomel
Yu. I. Yarets
Republican Research Center for Radiation Medicine and Human Ecology
Belarus
Belarus
Yuliya I. Yarets, Cand. Sc. (Medicine), Associate Professor, Head of the Clinical Laboratory Medicine Department, Gomel
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Review
For citations:
Silvistrovich V.I., Lyzikov A.A., Yarets Yu.I. Correlation between the level of bacterial load and clinical characteristics of the course of the disease in patients with neuroischaemic diabetic foot. Health and Ecology Issues. 2021;18(1):41-47. (In Russ.) https://doi.org/10.51523/2708-6011.2021-18-1-6
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