THE ROLE OF PLATELETS IN FORMATION OF NEUTROPHIL EXTRACELLULAR TRAPS IN PATIENTS WITH IMMUNOCOMPLEX PATHOLOGY
https://doi.org/10.51523/2708-6011.2016-13-3-14
Abstract
The article presents the results of the assessment of the role of platelets in formation of extracellular traps by neutrophils. We have detected the ability of platelets to oppress the formation of extracellular traps by neutrophils in vitro cultures in patients with rheumatoid arthritis (RA) (n = 42) and systemic lupus erythematosus (SLE) (n = 24), but not in patients with hemorrhagic vasculitis (GW) (n = 15). The study has revealed the interrelation of NETosis and rheumatoid factor in patients with RA and SLE, as well as NET formation and number of platelets in patients with GW.
About the Authors
J. V. Zubkova
Gomel State Medical University
Belarus
Belarus
I. A. Novikova
Gomel State Medical University
Belarus
Belarus
V. V. Zhelezko
Gomel State Medical University
Belarus
Belarus
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Review
For citations:
Zubkova J.V., Novikova I.A., Zhelezko V.V. THE ROLE OF PLATELETS IN FORMATION OF NEUTROPHIL EXTRACELLULAR TRAPS IN PATIENTS WITH IMMUNOCOMPLEX PATHOLOGY. Health and Ecology Issues. 2016;(3):66-70. (In Russ.) https://doi.org/10.51523/2708-6011.2016-13-3-14
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