Changes of the Biochemical Parameters of the Blood Serum of Wistar rats Exposed to Chronic Stres
https://doi.org/10.51523/2708-6011.2019-16-4-12
Abstract
Objective: to assess the effect of chronic nonspecific stress on changes of the biochemical parameters of the blood serum in male Wistar rats.
Material and methods. The experimental study was performed on sexually mature male Wistar rats. The experimental group (n = 71) was exposed to chronic nonspecific stress according to the Ortiz method. The control group of the animals included intact animals (n = 31).
Results. The study has revealed changes in the biochemical composition of the blood serum of the rats: increased activity of ALT, LDH, ALP, urea, uric acid, and cholesterol, a decreased level of triglycerides.
Conclusion. These changes may indicate the alteration of the level of the intensity of the physiological processes of energy supply in the conditions of chronic stress.
About the Authors
K. A. Kidun
Gomel State Medical University
Belarus
Belarus
Kidun K.A., senior lecturer of the Department of Biology with the courses of Normal and Pathological Physiology of the EI "Gomel State Medical University".
A. N. Litvinenko
Gomel State Medical University
Belarus
Belarus
Litvinenko A.N., senior lecturer of the Department of Biology with the courses of Normal and Pathological Physiology of the EI "Gomel State Medical University".
T. S. Ugolnik
Gomel State Medical University
Belarus
Belarus
Ugolnik T.S., PhD, Ass. Professor of the Department of Biology with the courses of Normal and Pathological Physiology of the EI "Gomel State Medical University".
N. M. Golubykh
Gomel State Medical University
Belarus
Belarus
Golubykh N.M., research officer of the Research Laboratory of the EI "Gomel State Medical University".
E. K. Solodova
Gomel State Medical University
Belarus
Belarus
Solodova E.K., PhD, Ass. Professor, Department of Histo-logy, Cytology and Embriology, EI "Gomel State Medical Uni-versity".
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Review
For citations:
Kidun K.A., Litvinenko A.N., Ugolnik T.S., Golubykh N.M., Solodova E.K. Changes of the Biochemical Parameters of the Blood Serum of Wistar rats Exposed to Chronic Stres. Health and Ecology Issues. 2019;(4):62-67. (In Russ.) https://doi.org/10.51523/2708-6011.2019-16-4-12
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