Preview

Health and Ecology Issues

Advanced search

ANTIBACTERIAL PROPERTIES OF NEW BIOLOGICALLY ACTIVE SURGICAL SUTURES

https://doi.org/10.51523/2708-6011.2014-11-2-20

Abstract

Objective: to evaluate the sorption potential of various antibiotics on polylactide and polypropylene surgical threads, whose surface is modified by direct radiation grafting of acrylic acid in the presence of N, N- methylene- bis- acrylamide, and antibacterial properties and capillarity of new surgical suture. Material and methods. The surface of the surgical sutures was modified by direct radiation grafting of acrylic acid. The bond strength of different antibacterial preparations was studied with modified threads. The antibacterial activity of the threads with Levofloxacin was studied against St.aureus, E.coli, Ps.aeruginosa . The capillarity of the modified surgical suture was studied. Results. The new surgical suture has a greater affinity to the fluoroquinolone antibiotics, has a pronounced antibacterial activity against E.coli, St.aureus, Ps.aeruginosa . Conclusion. The new surgical suture material can most effectively be used in surgery for prevention of infectious complications in the postoperative period.

About the Authors

A. S. Kniaziuk
Gomel State Medical University
Belarus


N. I. Shevchenko
Gomel State Medical University
Belarus


D. N. Bontsevich
Gomel State Medical University
Belarus


References

1. Соединение тканей в хирургии / Б. О. Мильков [и др.], под. ред. Б. О. Милькова. - Черновцы: Редакционно-издательский отдел облполнграфиздата, 1991. - 112 с.

2. Буянов, В. М. Хирургический шов / В. М. Буянов, В. Н. Егиев, О. А. Удотов - График Групп, 2000. - 93 с.

3. Байчоров, Э. Х. Современный шовный материал, приме-няемый в хирургии / Э. Х. Байчоров, Л. М. Дубовой, А. Д. Па-сечников // Здоровье - системное качество человека: сб. ст. - Ставрополь, 1999. - С. 328-334.

4. Ерюхин, И. А. Хирургические инфекции / И. А. Ерюхин, Б. Р. Гельфанд, С. А. Шляпников, под ред. И. А. Ерюхина. - СПб: Питер, 2003. - 864с.

5. Абаев, Ю. К. Раневая инфекция в хирургии / Ю. К. Абаев. - Минск: Беларусь, 2003. - 293 с.

6. Тец, В. В. Микроорганизмы и антибиотики. Сепсис / В.В. Тец. - СПб: Эскулап, 2003. - 154 с.

7. Antibiotic coating of abdominal suture and wound infection / C. Justinger [et al.] // Surgery. - 2009. - Vol. 145. - P. 330-334.

8. Katz, S. Bacterial adherenceto surgical sutures. A possible factor in suture induced infection / S. Katz, M. Izhar, D. Mirelman // Ann. Surgery. - 1981. - Vol. 194. - P. 35-41.

9. Are we really seeing the total cost of surgical site infection? A Spanish study / J. L. Alfonso [et al.] // Wound Repair Regen. - 2007. - V. 15. - P. 474-481.

10. Hoffman, A. S. Biomedical applications / A. S. Hoffman // Advanced radiation chemistry research: current status. IAEA. Vienna. - 1995. - P. 117-127.

11. Kabanov, V. Ya. Present status and development trends of radiation-induced graft polymerization / V. Ya. Kabanov, R. E. Aliev, Val. N. Kudryavtsev // Rad. Phys. Chem. - 1991. - Vol. 37. - P. 175-192.

12. Misra, G. P. In the biomedical arena / G. P. Misra, E. S. Gil, T. L. Lowe // Polymer grafting and crosslinking. - 2009. - P. 145-176.

13. Шатаева, Л. К. Карбоксильные катиониты в биологии / Л. К. Шатаева, Н. Н. Кузнецова, Г. Э. Елькин. - Ленинград: Наука, 1979. - 286 с.

14. Фторхинолоны: состав, строение и спектроскопические свойства / А. В. Полищук [и др.] // Вестник ДВО РАН. - 2005. - № 2. - С. 128-137.


Review

For citations:


Kniaziuk A.S., Shevchenko N.I., Bontsevich D.N. ANTIBACTERIAL PROPERTIES OF NEW BIOLOGICALLY ACTIVE SURGICAL SUTURES. Health and Ecology Issues. 2014;(2):96-100. (In Russ.) https://doi.org/10.51523/2708-6011.2014-11-2-20

Views: 288


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)