Analysis of Autopsy Results in Patients with Liver Cirrhosis over 2015-2018
https://doi.org/10.51523/2708-6011.2019-16-4-4
Abstract
Objective: to analyze the mortality structure of patients with liver cirrhosis over 2015-2018 in Gomel.
Material and methods. A retrospective cohort analysis of 130 findings of postmortem autopsy of patients with liver cirrhosis has been performed (data of the departments of Gomel Regional Pathology Bureau at Gomel Regional Infectious Clinical Hospital, Gomel City Clinical Hospital No. 3 and Gomel City Clinical Hospital No. 2, 2015-2018). The age and gender structure of the patients, etiology and cause of death were analyzed. The data were entered and analyzed in MS Excel, 2010.
Results. Most frequently, the patients with cirrhosis die at 50-59 and usually of hepatorenal syndrome (HRS), gastrointestinal bleeding, and acute posthemorrhagic anemia. Non-viral hepatitis as a cause of cirrhosis is more prevalent (61.5 %) than viral hepatitis, while the etiology for more than a third of the cirrhosis cases (38.5 %) is not determined. Most of the patients who died were of the working age (67.7 %) and mainly males (56.2 %). More than a third of the patients (38.5 %) had been dependent on alcohol, while only 11.5 % patients had been dia nosed with alcohol related cirrhosis.
Conclusion. Thus, liver cirrhosis is still a socially topical issue for young ablebodied people. There remains a tendency to underestimate the alcoholic etiology of cirrhosis, as well as the uncertainty of the etiology of a significant part of detected cirrhosis cases.
About the Authors
V. M. MitsuraBelarus
Mitsura V.M., DMedSci., Professor of the Department of Infectious Diseases of the EI «Gomel State Medical University».
A. G. Skuratov
Belarus
Skuratov A.G., PhD, Associate Professor of the Department of Surgical Diseases No.1 with the course of Cardiovascular Surgery of the educational institution «Gomel State Medical University».
V. A. Savarina
Belarus
Savarina V.A., Master, assistant of the Department of General and Clinical Pharmacology of the EI «Gomel State Medical University».
D. V. Tereshkov
Belarus
Tereshkov D.V., Head of the Infectious Diseases Ward No. 1 of the SHI «Gomel Regional Clinical Hospital of Infectious Diseases».
A. A. Poddubny
Belarus
Poddubny A.A., 5th year student of the Faculty of General Medicine of the EI «Gomel State Medical University».
References
1. Мицура ВМ. HCV-ассоциированный цирроз печени: клинические проявления и причины неблагоприятных исходов. Клин Инфектология и Паразитология. 2013;3(6):75-82.
2. Кучерявый ЮА, Стукова НЮ, Ахтаева МЛ. Хронический гепатит, цирроз печени и гепатоцеллюлярная карцинома - звенья одной цепи. Клин Перспект Гастроэнтерол Гепатол. 2012;5:3-11.
3. Смертность в Республике Беларусь. Официальный статистический сборник за 2015-2016 гг. Минск, Беларусь: РНМБ; 2017. 234 с.
4. Хазанов АИ, Плюснин СВ, Васильев А.П. Алкогольные и вирусные циррозы печени у стационарных больных (1996–2005 гг.): распространенность и исходы. Рос Журн Гастроэнтерол. 2007;2:9-27.
5. Michitaka K, Nishiguchi S, Aoyagi Y. Etiology of liver cirrhosis in Japan: a nationwide survey. J Gastroenterol. 2010;1(45):86-94.
6. Сухорук АА, Герасимова ЕВ, Эсауленко ОА. Цирроз печени как исход хронического гепатита С. Журн Инфектологии. 2014;1(6):67-71.
7. Мицура ВМ. Клиническая характеристика HCV-ассоциированного цирроза печени, скорость прогрессирования заболевания и влияние алкоголя. Мед Журн. 2013;4(46):79-82.
8. Kuntz E., Kuntz HD. Hepatology: Textbook And Atlas. Würzburg: Springer; 2008. 937 p.
9. Кучерявый ЮА, Оганесян ТC, Стукова НЮ. Гепатоцеллюлярная карцинома: взгляд врача общей практики. Consilium Medicum. 2011;1:38-41.
Review
For citations:
Mitsura V.M., Skuratov A.G., Savarina V.A., Tereshkov D.V., Poddubny A.A. Analysis of Autopsy Results in Patients with Liver Cirrhosis over 2015-2018. Health and Ecology Issues. 2019;(4):22-26. (In Russ.) https://doi.org/10.51523/2708-6011.2019-16-4-4