РЕЗУЛЬТАТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ РАКА ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ

Objective: to analyze the immediate and long-term results of surgery of pancreatic cancer (PC). Material and methods. The study included 97 patients with PC. 64 (66,0 %) patients underwent pancreaticoduodenectomy (PDE), 31 (31,9 %) - distal pancreatikosplenectomy (DPSE), 2 (2,1 %) patients underwent total pankreatikoduodenektomy (TPDE). Results. After DPSE, the postoperative morbidity and mortality were 9,6 and 3,2 %, respectively. After TPDE, there were no complications. The five-year actuarial survival rate among the patients after PDE made up 19,6 ± 5,5 %, after DPSE - 59,5 ± 9,6 % (P < 0,001). The lowest rates were observed in adenocarcinoma of the intestinal type (10,0 ± 8,8 %), ductal (21,9 ± 7,7 %) and mucin producing adenocarcinomas (30,0 ± 14,5 %), invasive mucinous cystadenocarcinoma (0 %), often localized in the head of the pancreas. 26,7 % of the patients after PDE revealed complications, 4.7 % died, the cause of death was failure of pancreatic anastomosis due to focal necrotizing pancreatitis. In 2 cases of neuroendocrine carcinoma there was multifocal lesion of the pancreatic gland, which demanded TDPE. One of the two patients having undergone TDPE was alive for 6 more years. Conclusion. The inadequate long-term results of the treatment of pancreatic head cancer are related to the predominance of aggressive forms of tumors and are indicative of the need to develop the methods of combined treatment.

рак поджелудочной железы, хирургическое лечение, осложнения, pancreatic cancer, surgery, complications

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