INFLUENCE OF MODIFIED ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE ON SYNOVIAL ENVIRONMENT OF JOINTS IN VIVO (experimental study)
https://doi.org/10.51523/2708-6011.2013-10-2-22
Abstract
Objective: evaluate the tribological properties of friction pair «modified UHMWPE-cartilage» and study the reactions of joint synovial tissue in the presence of UHMWPE with a microporous layer. Materials and methods. Tribological tests were carried out on an integrated-counting reciprocating tribometer and panel tests on the vibrotribometer of UHMWPE samples with a microporous layer and hyaline cartilage. To study the reactions of synovial tissue of the joint environ, we implanted modified UHMWPE samples into the knee joints of laboratory animals. 5, 14, 35 days after the implantation the condition of the synovial membrane and cartilage was assessed by morphometric method. Results. The smallest coefficient of friction was obtained in testing of friction pair «modified UHMWPE-cartilage» with blood serum. Adding blood serum as a lubricant in the friction pair «normal cartilage-UHMWPE» and «metal cartilage» leads to an increased friction coefficient. Based on the data of the histological examination, monitoring did not define any pathological changes in the synovial membranes and articular cartilage by day 35. Conclusion. The study showed that the friction coefficient of the pair «modified UHMWPE-cartilage» was slightly higher than that in the pair of «cartilage-cartilage» in comparable wear resistance. As a result of the implantation of the modified UHMWPE exudative-alterative reactions developed, but by the 35-th day of the monitoring no pathological changes were detected.
About the Authors
D. V. Charnashtan
Gomel State Medical University
Belarus
Belarus
V. I. Nikolayev
Gomel State Medical University
Belarus
Belarus
E. A. Nadyrov
Gomel State Medical University
Belarus
Belarus
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Review
For citations:
Charnashtan D.V., Nikolayev V.I., Nadyrov E.A. INFLUENCE OF MODIFIED ULTRAHIGH MOLECULAR WEIGHT POLYETHYLENE ON SYNOVIAL ENVIRONMENT OF JOINTS IN VIVO (experimental study). Health and Ecology Issues. 2013;(2):118-124. (In Russ.) https://doi.org/10.51523/2708-6011.2013-10-2-22
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