FECAL LACTOFERRIN IN DETECTION OF COLON CANCER AT VARIOUS STAGES OF ITS DEVELOPMENT
https://doi.org/10.51523/2708-6011.2012-9-4-19
Abstract
The purpose of the study was to evaluate the efficacy of detection of colorectal cancer at different stages of its development on the basis of fecal lactoferrin. Subject of study: 48 patients with colorectal cancer, 46 patients with irritable bowel syndrome and 25 healthy volunteers were included in the study group. The results of the study: it was found that fecal lactoferrin was diagnostically reliable with areas under the curve (AUC) at 0,940 ± 0,0327 and AUC: 0,956 ± 0,032, respectively in non-invasive diagnosis of early and late-stage colorectal cancer, and was not inferior to the immunochemical test for faecal occult blood (AUC: 0,939 ± 0,0342 and AUC: 0,931 ± 0,0393, p = 0,73 and p = 0,62,respectively).
About the Authors
E. I. Mihaylova
Gomel State Medical University
Belarus
Belarus
N. V. Filipenko
Gomel State Medical University
Belarus
Belarus
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Review
For citations:
Mihaylova E.I., Filipenko N.V. FECAL LACTOFERRIN IN DETECTION OF COLON CANCER AT VARIOUS STAGES OF ITS DEVELOPMENT. Health and Ecology Issues. 2012;(4):98-102. (In Russ.) https://doi.org/10.51523/2708-6011.2012-9-4-19
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