THE SKIN REGENERATION FEATURES IN APPLICATION OF MULTIPOTENT MESENCHYMAL STEM CELLS FROM ADIPOSE TISSUE OF LABORATORY ANIMALS WITH SOFT TISSUE DEFECTS
https://doi.org/10.51523/2708-6011.2012-9-2-26
Abstract
The paper presents the results of experimental studies in laboratory animals with a simulated infected wound. Their treatment included the application of mesenchymal stem cells (MSCs) derived from adipose tissue. It was established that the application of MSCs was accompanied by the regeneration features of skin defects, i.e. the inflammation was cut short faster, the wound healing processes accelerated, as well as the stimulation of growth of skin appendages was observed. The received results may be used as a basis for further research and development aimed at the introduction of cellular technologies for the treatment of wound defects of various etiology into clinical practice.
About the Authors
A. . Sahab Haidar
Belarusian State Medical University, Minsk
Belarus
Belarus
S. I. Tretiak
Belarusian State Medical University, Minsk
Belarus
Belarus
M. K. Nedzved
Belarusian State Medical University, Minsk
Belarus
Belarus
E. V. Baranov
nstitute of Biophysics and Cell Engineering of the National Academy of Sciences, the Republic of Belarus, Minsk
Belarus
Belarus
E. A. Nadyrov
Republican Research Center for Radiation Medicine and Human Ecology, Gomel
Belarus
Belarus
E. S. Lobanok
nstitute of Biophysics and Cell Engineering of the National Academy of Sciences, the Republic of Belarus, Minsk
Belarus
Belarus
I. B. Vasilevich
Institute of Biophysics and Cell Engineering of the National Academy of Sciences, the Republic of Belarus, Minsk
Belarus
Belarus
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Review
For citations:
Sahab Haidar A., Tretiak S.I., Nedzved M.K., Baranov E.V., Nadyrov E.A., Lobanok E.S., Vasilevich I.B. THE SKIN REGENERATION FEATURES IN APPLICATION OF MULTIPOTENT MESENCHYMAL STEM CELLS FROM ADIPOSE TISSUE OF LABORATORY ANIMALS WITH SOFT TISSUE DEFECTS. Health and Ecology Issues. 2012;(2):134-139. (In Russ.) https://doi.org/10.51523/2708-6011.2012-9-2-26
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