HEMOSTASIS ABNORMALITIES IN HYPERHOMOCYSTEINEMIA
https://doi.org/10.51523/2708-6011.2011-8-2s-35
Abstract
339 patients with cardiovascular pathology and 260 persons of the control group have been examined. The level of homocystein in plasma was measured by means of liquid chromatography under high pressure with fluorescent detection. The indicators of plasmic and thrombocyte hemostasis in the patients with normal or heightened level of plasma homocystein were compared. According to the obtained data, the increase of the homocystein level plays an important role in the formation of hypercoagulation syndrome. The presence of hyperhomocysteinemia leads to the development of endothelial dysfunction, activation of coagulation and thrombocyte parts of hemostasis, decrease of natural anticoagulants and fibrinolysis activity
About the Authors
V. M. Shmeliova
Russian Research Institute for Hematology and Transfusiolog
Belarus
Belarus
N. B. Saltykova
Russian Research Institute for Hematology and Transfusiolog
Belarus
Belarus
L. P. Papayan
Russian Research Institute for Hematology and Transfusiolog
Belarus
Belarus
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Review
For citations:
Shmeliova V.M., Saltykova N.B., Papayan L.P. HEMOSTASIS ABNORMALITIES IN HYPERHOMOCYSTEINEMIA. Health and Ecology Issues. 2011;(2S):97-100. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-2s-35
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