EXPERIENCE AND PROSPECTS OF THE CLINICAL APPLICATION OF MESENCHYMAL STEM CELLS

Tandem transplantation of hemopoeitic and mesenchymal stem cells is a perspective and now widely used direction of cell therapy of oncohematological diseases and multiple sclerosis in the clinical practice of the Republic of Belarus. Mesenchymal stem cells are also effectively used as concomitant immunosuppressive therapy of acute and chronic reaction Transplant Against Host (RTAH). The protocols of the application of mesenchymal stem cells for the therapy of oncohematological patients and patients with multiple sclerosis are approved by the Ministry of Public Health Care of the Republic of Belarus. The efficacy of the cell therapy with the use of mesenchymal stem cells is studied in the clinical research in the treatment for various diseases: genetic degenerative diseases of skeleton, ischemic disease, liver cirrhosis, neurodegenerative diseases (parkinsonism, Alzheimer's disease). The experimental work and clinical trials have shown the positive effect of the transplantation of mesenchymal stem cells in myocardial infarction and in the substitutive therapy of liver impairment.

стволовые клетки, трансплантация мезенхимальных стволовых клеток, реакция «трансплантат против хозяина», рассеянный склероз, кардиомиопластика, заболевания печени, stem cells, transplantation of mesenchymal stem cells, reaction «Transplant Against Host», multiple sclerosis, cardiomyoplasty, diseases of liver, stem cells, transplantation of mesenchymal stem cells, reaction «Transplant Against Host», multiple sclerosis, cardiomyoplasty, diseases of liver, стволовые клетки, трансплантация мезенхимальных стволовых клеток, реакция «трансплантат против хозяина», рассеянный склероз, кардиомиопластика, заболевания печени

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