ФОРМИРОВАНИЕ СОЕДИНИТЕЛЬНОЙ ТКАНИ ПРИ ПОСТИНФАРКТНОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ В НЕПОВРЕЖДЕННОЙ ЧАСТИ МИОКАРДА У ЭКСПЕРИМЕНТАЛЬНЫХ ЖИВОТНЫХ
https://doi.org/10.51523/2708-6011.2011-8-4-19
Abstract
The effect of postinfarction cardiac insufficiency of angiotensin II (AG-II) and interleukin-6 (IL-6) on the formation of connective tissue in the intact myocardium of the left ventricle of the heart has been studied in 8-week-old laboratory mice. It has been established that AG-II and IL-6 in postinfarction cardiac insufficiency have no effect both on the area, and the percentage of the connective tissue in the intact myocardium of the left ventricle of the heart in the experimental animals. In postinfarction cardiac insufficiency the antagonist of AT1 receptor telmisartan increases myocardial contractility of the myocardium of the left ventricle by 26,3 % (p <0,05), without affecting the area and the percentage of the connective tissue in the myocardium of the left ventricle of the heart in the experimental animals.
About the Authors
S. N. Litvinovich
Grodno State Medical Unievrsity
Belarus
Belarus
I. P. Yorsh
Grodno State Medical Unievrsity
Belarus
Belarus
A. V. Rakov
Grodno State Medical Unievrsity
Belarus
Belarus
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Review
For citations:
Litvinovich S.N., Yorsh I.P., Rakov A.V. . Health and Ecology Issues. 2011;(4):101-110. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-4-19
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